Switchable Fluorophores for Single-Molecule Localization Microscopy

Chemical Reviews
Honglin Li, Joshua C Vaughan

Abstract

The past decade has witnessed an explosion in the use of super-resolution fluorescence microscopy methods in biology and other fields. Single-molecule localization microscopy (SMLM) is one of the most widespread of these methods and owes its success in large part to the ability to control the on-off state of fluorophores through various chemical, photochemical, or binding-unbinding mechanisms. We provide here a comprehensive overview of switchable fluorophores in SMLM including a detailed review of all major classes of SMLM fluorophores, and we also address strategies for labeling specimens, considerations for multichannel and live-cell imaging, potential pitfalls, and areas for future development.

References

Jan 1, 1983·Annual Review of Biochemistry·A Meister, M E Anderson
Jun 25, 1996·Proceedings of the National Academy of Sciences of the United States of America·T HaS Weiss
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·M ChattorajS G Boxer
Nov 22, 1997·Current Biology : CB·K E Sawin, P Nurse
Nov 22, 1997·Current Biology : CB·M B ElowitzS Leibler
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·M A BoppR M Hochstrasser
May 22, 1989·Physical Review Letters·W E Moerner, L Kador
Aug 12, 1999·Journal of Microscopy·M G GustafssonJ W Sedat
Jul 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·T A KlarS W Hell
Aug 22, 2001·Bioorganic & Medicinal Chemistry Letters·K R GeeD J Kozlowski
Sep 18, 2001·Methods : a Companion to Methods in Enzymology·T Ha
Dec 26, 2001·Chemical Reviews·R C Dunn
Jan 5, 2002·Chemical Reviews·Masahiro Irie
Apr 20, 2002·Biophysical Journal·Russell E ThompsonWatt W Webb
Sep 5, 2002·Nature Reviews. Cancer·Sanjiv Sam Gambhir
Sep 14, 2002·Science·George H Patterson, Jennifer Lippincott-Schwartz
Sep 25, 2002·Proceedings of the National Academy of Sciences of the United States of America·Ryoko AndoAtsushi Miyawaki
Dec 7, 2002·Nature Biotechnology·Antje KepplerKai Johnsson
Jan 14, 2003·Nature Biotechnology·Dmitriy M ChudakovKonstantin A Lukyanov
Jan 30, 2003·Journal of the American Chemical Society·Katherine A WilletsW E Moerner
Dec 20, 2003·Science·Ahmet YildizPaul R Selvin
Feb 10, 2004·Chemical Society Reviews·He Tian, Songjie Yang
Apr 21, 2004·Proceedings of the National Academy of Sciences of the United States of America·Matthew P GordonPaul R Selvin
Jul 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Xiaohui QuNorbert F Scherer
Oct 27, 2004·Nature Biotechnology·Dmitriy M ChudakovKonstantin A Lukyanov
Oct 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jörg WiedenmannG Ulrich Nienhaus
Jan 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·L Stirling ChurchmanJames A Spudich
Feb 26, 2005·EMBO Reports·Hidekazu TsutsuiAtsushi Miyawaki
Mar 18, 2005·Journal of the American Chemical Society·Mike HeilemannPhilip Tinnefeld
Mar 23, 2005·Nature Methods·Lawrence W MillerVirginia W Cornish
Mar 24, 2005·Physical Review Letters·Mark BatesXiaowei Zhuang
Mar 31, 2005·Chemistry & Biology·Vladislav V Verkhusha, Alexander Sorkin
May 18, 2005·Proceedings of the National Academy of Sciences of the United States of America·Mark HowarthAlice Y Ting

❮ Previous
Next ❯

Citations

Aug 9, 2019·Angewandte Chemie·Dmytro I DanylchukAndrey S Klymchenko
Oct 2, 2019·Organic & Biomolecular Chemistry·Taylor A NealJovica D Badjić
Sep 14, 2019·Chemistry : a European Journal·Joshua K G KarlssonAnthony Harriman
Oct 9, 2019·Nature Communications·Michelle S FreiKai Johnsson
Dec 11, 2019·Nature Methods·Jelmer CnossenSjoerd Stallinga
Apr 24, 2020·Methods and Applications in Fluorescence·Yang Zhang, Françisco M Raymo
Apr 28, 2020·Chemistry : a European Journal·Juraj GaletaMilan Vrabel
Jul 16, 2020·Bio-protocol·Julia K DohKimberly E Beatty
Jul 11, 2020·Beilstein Journal of Organic Chemistry·Kazuyuki SatoMasaaki Omote
Jun 13, 2020·Journal of Cell Science·Guillaume JacquemetChristophe Leterrier
Jul 17, 2020·Angewandte Chemie·Xiao-Jun TangXiaohong Fang
Jun 26, 2020·Frontiers in Plant Science·Tereza VavrdováGeorge Komis
Aug 7, 2020·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·E Abou NakadA Specht
Mar 4, 2021·Experimental & Molecular Medicine·Yeonho ChangSung Ho Ryu
Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shunsuke TakahashiShinji Katsura
Mar 14, 2021·Nature Reviews. Neuroscience·Daniel ChoquetJean-Baptiste Sibarita
Aug 25, 2020·Trends in Cell Biology·Yu-Le WuJonas Ries
Mar 26, 2021·Methods and Applications in Fluorescence·Esther L MiriklisDonna R Whelan
Jun 5, 2021·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Elena A ProtasovaAlexey M Bogdanov
Jun 8, 2021·The Journal of Physical Chemistry. B·Lexy von Diezmann, Ofer Rog
May 18, 2021·Frontiers in Chemistry·Xiaoyu Cheng, Wei Yin
May 21, 2021·The Journal of Biological Chemistry·Jessica ValliColin Rickman
Jun 25, 2021·Quarterly Reviews of Biophysics·David J DeRosier
Oct 2, 2019·ACS Central Science·Kimberly E Beatty
May 29, 2020·Organic Letters·Junliang ZhouWeili Zhao
Apr 19, 2019·ACS Chemical Biology·Fadi M Jradi, Luke D Lavis
Dec 19, 2019·The Journal of Organic Chemistry·Futa OgawaMasaaki Omote
Sep 22, 2020·Journal of the American Chemical Society·Xianzhi ChaiHe Tian
Oct 31, 2020·Chemical Reviews·Roy WeinstainPetr Klán

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Methods in Cell Biology
Jennifer C Waters
The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Ellen C Jensen
© 2022 Meta ULC. All rights reserved