PMID: 3770263Jan 1, 1986Paper

Symmetrical peripheral gangrene in disseminated tuberculosis

Dermatologica
P ItinW Vischer

Abstract

We report the case of a 66-year-old man who developed a symmetrical peripheral gangrene (SPG) on both feet during disseminated miliary tuberculosis. Mycobacterium tuberculosis was not only isolated from sputum, gastric juice, and urine, but also from a blood culture. Since a disseminated intravascular coagulopathy was very likely to be excluded, it is possible that the SPG was due to embolization of arterioles by the tubercle bacilli. The literature of SPG is reviewed and the different possible pathogenic mechanisms of SPG, such as hypoxemia, vasoconstriction, primary endothelial damage, and vascular obstruction, are discussed. SPG is another cutaneous manifestation of disseminated tuberculosis.

Citations

Jan 26, 2011·QJM : Monthly Journal of the Association of Physicians·C-F ChenY-F Wei
Mar 12, 2011·Indian Journal of Dermatology, Venereology and Leprology·Sudip Kumar Ghosh, Debabrata Bandyopadhyay
Jan 17, 2017·Tropical Doctor·Ankit JainVir Singh Negi
Nov 25, 2017·International Journal of Mycobacteriology·Tushar PatialSunil Negi

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