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Sympathectomy or doxazosin, but not propranolol, blunt myocardial interstitial fibrosis in pressure-overload hypertrophy

Hypertension

Nov 1, 2005

Stefano PerliniAlberto U Ferrari

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Abstract

The adaptive changes that develop in the pressure-overloaded left ventricular (LV) myocardium include cardiomyocyte hypertrophy and interstitial fibrosis. Although the former is known to depend to a sizeable extent on sympathetic (over)activity, little information exists whether the sam...read more

Mentioned in this Paper

Salicylhydroxamic acid
Tissue Inhibitor of Metalloproteinase-2
Left Ventricular Hypertrophy
Hypertrophy
Blood Pressure
Zyderm
Metalloproteases
MMP-2 Activity
Propranolol
Cirrhosis
Paper Details
References
  • References19
  • Citations33
12
  • References19
  • Citations33
1234

Sympathectomy or doxazosin, but not propranolol, blunt myocardial interstitial fibrosis in pressure-overload hypertrophy

Hypertension

Nov 1, 2005

Stefano PerliniAlberto U Ferrari

PMID: 16216989

DOI: 10.1161/01.hyp.0000185689.65045.4c

Abstract

The adaptive changes that develop in the pressure-overloaded left ventricular (LV) myocardium include cardiomyocyte hypertrophy and interstitial fibrosis. Although the former is known to depend to a sizeable extent on sympathetic (over)activity, little information exists whether the sam...read more

Mentioned in this Paper

Salicylhydroxamic acid
Tissue Inhibitor of Metalloproteinase-2
Left Ventricular Hypertrophy
Hypertrophy
Blood Pressure

Related Papers

Paper Details
References
  • References19
  • Citations33
12
  • References19
  • Citations33
1234

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