Sympathetic ophthalmia after surgical resection of iridociliary melanoma. A case report

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Jose Garcia-ArumiAntonio Segura Garcia

Abstract

We report a case of sympathetic ophthalmia with systemic findings following resection of a malignant melanoma of the iris and ciliary body, and describe the treatment and clinical outcome. A 49-year-old man underwent sector iridocyclectomy of a malignant iridociliary melanoma of the right eye. Five weeks later, he was diagnosed with sympathetic ophthalmia. Snellen's best-corrected visual acuity, fluorescein angiography, electroretinography, cerebrospinal fluid analysis and audiometry were performed. High-dose systemic steroid and immunosuppressive (cyclosporine and azathioprine) therapy was prescribed. Two months later chorioretinitis and macular edema persisted, and intravitreous triamcinolone was injected into the right eye. Five weeks after resection of an iridociliary melanoma, our patient had reported acute bilateral vision loss. Visual acuity was hand motion in both eyes. Examination showed bilateral granulomatous uveitis, diffuse choroiditis with Dalen-Fuchs nodules, papillitis and vitritis. On fluorescein angiography multiple hyperfluorescent dots, which coalesced in areas of exudative retinal detachment, were evident. The patient presented meningismus with pleocytosis on cerebrospinal fluid analysis, and sensorineural ...Continue Reading

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Citations

Sep 17, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Claudia Patricia Castiblanco, Ron A Adelman
Apr 2, 2013·American Journal of Ophthalmology·Christopher Seungkyu LeeSung Chul Lee
Jul 17, 2009·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Hatem KremaHugh McGowan
Sep 21, 2013·Ophthalmic Surgery, Lasers & Imaging Retina·Ekaterina Semenova, Paul T Finger
Dec 1, 2007·International Ophthalmology Clinics·Robin Ray, Rod Foroozan
Jan 1, 2019·Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti·J KrásnýH Šubrtová
Aug 23, 2020·Indian Journal of Ophthalmology·Gazal PatnaikJyotirmay Biswas

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