PMID: 8600483Nov 1, 1995Paper

Sympathetic reactivity to acute stress and immune response in women

Psychosomatic Medicine
K A MatthewsA L Miller

Abstract

We evaluated if the effects of acute stress on immune parameters were apparent in only the women who showed concomitant and substantial sympathetic nervous system activation and after statistical adjustment for changes in plasma volume. Nineteen women in the follicular stage of their menstrual cycles were assessed for immunological responsiveness to a series of three 3-minute psychological tasks, which reliably elicit cardiovascular and neuroendocrine stress responses. Women were classified as high or low sympathetic reactors based on their cardiovascular and neuroendocrine responses to one of the three tasks, a public speaking task. The stress-induced decreases in CD4+ percentage and increases in natural killer cell number and cytolytic activity were only apparent among the high reactors. Further analysis adjusting for alterations in plasma volume changes showed that the increase in NK cell number remained. Stress-induced proliferative responses to pokeweed mitogen and phytohemagglutinin were not more apparent among high reactors. These results are consistent with the hypothesis that the sympathetic nervous system plays a direct role in modulating the short term response to stress of some indices of the immune system in women.

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References

Jan 1, 1992·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·S G ZakowskiA Baum
Nov 1, 1992·Psychosomatic Medicine·E A BachenB S Rabin
Mar 1, 1992·Psychosomatic Medicine·P H KnappT C Heeren
Mar 1, 1991·Psychosomatic Medicine·B D NaliboffS L Gilmore
Jan 1, 1990·Journal of Clinical Laboratory Analysis·T L WhitesideR B Herberman
Oct 1, 1989·Archives of General Psychiatry·C G McAllisterS M Paul
Jan 1, 1989·British Journal of Haematology·C JernS Jern
Dec 1, 1983·Journal of Health and Social Behavior·S CohenR Mermelstein
Jul 1, 1995·Psychosomatic Medicine·E A BachenB S Rabin
Nov 1, 1993·Psychosomatic Medicine·M T AllenK A Matthews
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH

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Citations

Jul 15, 2004·Psychological Bulletin·Suzanne C Segerstrom, Gregory E Miller
Mar 13, 2001·The American Psychologist·R M Suinn
Jul 10, 1999·Psychoneuroendocrinology·P BorellaG Vivoli
Mar 21, 2007·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Maureen ShannonHolly Powell Kennedy
Oct 18, 2011·Brain, Behavior, and Immunity·Emanuela Offidani, Chiara Ruini
Nov 16, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J CwikelE Sheiner
Jun 18, 2004·The Journal of Urology·Susan K LutgendorfKarl J Kreder
Sep 19, 2000·The Journal of Urology·S K LutgendorfB Zimmerman
Sep 25, 2003·Alcoholism, Clinical and Experimental Research·Nancy C BernardyWilliam R Lovallo
Aug 10, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S RietveldT L Creer
May 22, 2001·Journal of Medical Virology·O SaridM Margalith
Apr 20, 2013·Stress : the International Journal on the Biology of Stress·Qing LiuYanfeng Liu
May 31, 2001·Psychosomatic Medicine·H L LoganD Lubaroff
Jan 31, 2002·Psychosomatic Medicine·Janice K Kiecolt-GlaserRonald Glaser
Jun 27, 2008·Pharmacological Reviews·Virginia M Miller, Sue P Duckles
Jan 17, 2004·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Lisa KalmanRebecca Buckley
Nov 21, 2007·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Cheryl RegehrJoanne Daciuk
Aug 12, 1999·Psychosomatic Medicine·M L PetersC J Heijnen
Jul 18, 2001·Journal of Applied Physiology·J T NoteboomR M Enoka
Dec 29, 1999·Medicine and Science in Sports and Exercise·P A DeusterE M Sternberg
Jul 5, 2002·Brain, Behavior, and Immunity·Virginia M Sanders, Rainer H Straub

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