PMID: 9416721Jan 7, 1998Paper

Sympathovagal effects of spinal anesthesia assessed by the spontaneous cardiac baroreflex

Anesthesiology
P GratadourL Quintin

Abstract

The changes in sympathovagal balance induced by spinal anesthesia remain controversial. The spontaneous baroreflex method allows the continuous assessment of the spontaneous engagement of the cardiac baroreflex, giving an index of sympathovagal balance. The purpose of this study was to follow the effects of spinal anesthesia on spontaneous baroreflex sensitivity. Continuous electrocardiogram and noninvasive blood pressure were recorded in 24 patients scheduled for elective inguinal hernia repair and randomly assigned to three groups: (1) no volume loading, (2) volume loading of 15 ml/kg lactated Ringer's solution, and (3) continuous infusion of etilefrine (an ephedrine-like drug). Each patient was studied before, during, and after bupivacaine-induced spinal anesthesia (mean sensory block: T4). Spontaneous baroreflex sensitivity and parameters of time-domain analysis of heart rate variability were calculated from 30 min of recording of each period. No significant change in spontaneous baroreflex slope or parameters of time-domain analysis were observed after regional anesthesia in any group. However, three patients experienced episodes of bradycardia and hypotension in the absence of a high block; these three patients showed an ...Continue Reading

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Citations

Nov 25, 2004·Anesthesia and Analgesia·Dmitri ChamchadJ Yasha Kresh
Oct 8, 2003·Best Practice & Research. Clinical Anaesthesiology·Francis V SalinasSpencer S Liu
Oct 5, 2006·Current Opinion in Anaesthesiology·Andrea Casati, Federico Vinciguerra
Apr 30, 2003·Anesthesiology·Jason A Campagna, Christopher Carter
Jun 5, 2001·Anesthesiology·S S Liu, S B McDonald
Jan 31, 2002·Anesthesiology·John B Pollard
Aug 21, 2007·International Journal of Cardiology·P GratadourL Quintin
Apr 27, 2007·International Journal of Obstetric Anesthesia·F BrenckA Junger
Sep 9, 2004·Acta Anaesthesiologica Scandinavica·M Tanaka, T Nishikawa
Aug 28, 2009·Veterinary Anaesthesia and Analgesia·Francesco StaffieriAntonio Crovace
Apr 12, 2000·European Journal of Anaesthesiology·A BouaggadO Abassi
Nov 22, 2002·European Journal of Anaesthesiology·M Kamenik
Feb 22, 2011·Revista brasileira de anestesiologia·Juliana Arruda Godoy Limongi, Rossana Sant'anna de Melo Lins

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