Symptom Burden in the First Year After Cancer Diagnosis: An Analysis of Patient-Reported Outcomes

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Lev D BubisNatalie G Coburn

Abstract

Purpose Improvement in the quality of life of patients with cancer requires attention to symptom burden across the continuum of care, with the use of patient-reported outcomes key to achieving optimal care. Yet there have been few studies that have examined symptoms in the early postdiagnosis period during which suboptimal symptom control may be common. A comprehensive analysis of temporal trends and risk factors for symptom burden in newly diagnosed patients with cancer is essential to guide supportive care strategies. Methods A retrospective observational study was performed of patients who were diagnosed with cancer between January 2007 and December 2014 and who survived at least 1 year. Patient-reported Edmonton Symptom Assessment System scores, which are prospectively collected at outpatient visits, were linked to provincial administrative health care data. We described the proportion of patients who reported moderate-to-severe symptom scores by month during the first year after diagnosis according to disease site. Multivariable logistic regression models were constructed to identify risk factors for moderate-to-severe symptom scores. Results Of 120,745 patients, 729,861 symptom assessments were recorded within 12 months o...Continue Reading

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Citations

May 10, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicole M Kuderer, Gary H Lyman
Dec 27, 2019·Psycho-oncology·Peter HerschbachBirgitt Marten-Mittag
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