PMID: 11898144Mar 20, 2002Paper

Symptom profile of nasopharyngeal cancer patients during radiation therapy

Cancer Practice
H Y HuangL L Ting

Abstract

This prospective, longitudinal study was aimed to describe the prevalence, severity, and pattern of symptoms over the course of radiation therapy in persons with nasopharyngeal carcinoma and to explore symptom severity by treatment modality. Thirty-seven patients completed this study, and 46% received chemotherapy before radiation therapy. A self-reported radiation symptom checklist and an objective mucositis assessment tool were used weekly to document oropharyngeal, skin, nose or ear, or more general side effects, and mucositis. Oropharyngeal problems were the most severe complaints during radiation therapy. All patients experienced dry mouth, taste change, difficulty in swallowing, difficulty in opening their mouths, hoarseness, sore throat, and observable mucositis. Most reported moderate-to-severe dry mouth, difficulty in swallowing, and sore throat from weeks 3 through 7. Skin problems were not prominent until week 4. Patients also lost an average of 3.9 kg during the therapy. Sequential chemotherapy and radiation therapy was associated with more severe oropharyngeal problems than radiation therapy alone, but no significant differences in other problems were found. Despite recognition of the oropharyngeal side effects ass...Continue Reading

References

Oct 1, 1985·International Journal of Radiation Oncology, Biology, Physics·S C HuangT C Lynn
Apr 1, 1985·Journal of Personality and Social Psychology·B L Andersen, H H Tewfik
Apr 1, 1980·International Journal of Radiation Oncology, Biology, Physics·S C Huang
Jul 1, 1995·Current Opinion in Oncology·W Carl
May 1, 1995·Current Opinion in Oncology·P M Harari, T J Kinsella
May 1, 1995·Current Opinion in Oncology·A Fandi, E Cvitkovic
Aug 30, 1994·International Journal of Radiation Oncology, Biology, Physics·T A MakkonenH Joensuu
Jan 1, 1993·Epidemiologic Reviews·A Hildesheim, P H Levine
Jan 1, 1997·Oral Oncology·S H ShiehC C Tseng
Feb 18, 1998·Current Opinion in Oncology·E Estey
Jul 4, 1998·British Journal of Cancer·R P Symonds
Jul 24, 1998·CA: a Cancer Journal for Clinicians·B Vikram
Feb 3, 2000·International Journal of Radiation Oncology, Biology, Physics·N JhaL Coulter
Mar 4, 2000·International Journal of Radiation Oncology, Biology, Physics·E Y HuangC Y Hsiung
Mar 22, 2000·International Journal of Radiation Oncology, Biology, Physics·J BourhisF Eschwege

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Citations

May 25, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Allan J HovanUNKNOWN Dysgeusia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Socie
Mar 5, 2003·Journal of Pain and Symptom Management·Hsiu-Ying HuangLai-Lei Ting
Oct 6, 2010·Cancer Nursing·Pei-Ling TangHuey-Shyan Lin
Jul 2, 2002·Journal of Consulting and Clinical Psychology·Barbara L Andersen
Mar 20, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·S B JensenUNKNOWN Salivary Gland Hypofunction/Xerostomia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cance
Aug 27, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Lindsay BrownHadi Seikaly
Dec 25, 2007·Dental Clinics of North America·Michael T BrennanPeter B Lockhart
Sep 4, 2007·International Journal of Radiation Oncology, Biology, Physics·Bee-Horng LueHsiu-Jung Chen
Apr 17, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Mo-Fa GuYuan-Ming Diao
Aug 23, 2005·Head & Neck·Sarah J LovellJanet A Wilson
Jul 20, 2021·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Wenli XiaoKa Ming Chow

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