Symptomatic hepatic cysts: treatment with single-shot injection of minocycline hydrochloride

Radiology
C CellierG Frija

Abstract

To assess the efficacy of percutaneous minocycline hydrochloride sclerotherapy in symptomatic hepatic cysts. From November 1992 to June 1994, seven of eight consecutive adults with large symptomatic hepatic cysts (diameter, 55-130 mm) were treated with a single intracystic injection of minocycline hydrochloride in an ambulatory procedure. Five patients had a solitary cyst, and two had polycystic liver disease. The target cyst was punctured under ultrasound guidance and local anesthesia with a 22-gauge Chiba needle. Half of the cyst content was aspirated before injection of 100-500 mg of minocycline hydrochloride diluted in 5-25 mL of saline. The minocycline hydrochloride was left in the cyst at the end of the procedure. After a mean follow-up of 28 months (range, 24-42 months), all five patients with solitary cysts were asymptomatic and four had documented complete cyst regression; the two patients with multiple hepatic cysts showed only transient clinical improvement. Single-shot injection of minocycline hydrochloride is an effective treatment for symptomatic solitary hepatic cysts but is less effective in polycystic liver disease.

Citations

Nov 15, 2006·Southern Medical Journal·C PalaniveluVijaykumar Malladi
Feb 11, 2014·Journal of Gastrointestinal Cancer·Gaetano BertinoIsidoro Di Carlo
Jun 10, 2000·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·M B WimmershoffM Landthaler
Nov 9, 2004·Surgical Endoscopy·T N RobinsonG T Everson
Jul 28, 2007·Pediatric Surgery International·Takeshi AoyagiSatoru Todo
Dec 13, 2006·Digestive Diseases and Sciences·G GarceaD P Berry
Sep 1, 2005·Cardiovascular and Interventional Radiology·Kiyosei YamamotoHideo Uchida
Mar 8, 2011·Journal of Vascular and Interventional Radiology : JVIR·Miho YamakawaKazuhiro Iwase
Oct 27, 2009·Journal of Vascular and Interventional Radiology : JVIR·Hiroyasu FujiwaraSusumu Kanazawa
Apr 19, 2003·Journal of Gastroenterology and Hepatology·Hiroshi YoshidaKoho Akimaru
Apr 28, 2012·ANZ Journal of Surgery·Giuseppe GarceaAshley R Dennison
Jan 20, 2015·Asian Journal of Endoscopic Surgery·Mami KanamotoMitsuo Shimada
Jun 9, 2018·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yuji EsoHiroshi Seno
Jun 19, 2016·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Takashi IijimaYoshifumi Ubara
Feb 9, 2010·Revista do Colégio Brasileiro de Cirurgiões·Orlando Jorge Martins TorresGlaucia Mesquita Cordeiro
Aug 25, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Alicia FurumayaUNKNOWN Dutch Benign Liver Tumor Group

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