PMID: 3749811Aug 1, 1986Paper

Symptomatic recurrence of healed duodenal and prepyloric ulcers after treatment with ranitidine or high-dose antacid. A 1-year follow-up study

Scandinavian Journal of Gastroenterology
P BytzerJ Rask-Madsen

Abstract

Eighty-seven patients with duodenal (n = 49) or prepyloric (n = 38) ulcers healed with ranitidine (n = 44) or a high-dose liquid antacid (n = 43) completed a 1-year double-blind comparative study of symptomatic relapse without treatment. Both duodenal ulcers and prepyloric ulcers tended to remain true to their type of recurrence. Age, sex, history of ulcer disease, duration of initial treatment, and smoking habits were all without influence on the relapse rates. The subgroup of patients with a duodenal ulcer who had healed on either treatment regimen had a symptomatic relapse significantly more frequently than those with prepyloric ulcer (64% +/- 13 versus 34% +/- 15; p less than 0.025), but the estimated probabilities of relapse were unaffected (p greater than 0.05) by the initial type of medication (ranitidine group, 56% +/- 15; antacid group, 51% +/- 15). Thus the present study could not confirm the hypothesis that patients treated with H2-receptor antagonists tend to relapse earlier than those treated with antacids during the following year without treatment.

References

Apr 1, 1982·Scandinavian Journal of Gastroenterology·I N MarksA H Girdwood
Jan 1, 1981·Scandinavian Journal of Gastroenterology·M StrömA Walan
Jan 1, 1981·Scandinavian Journal of Gastroenterology·A BerstadE Carlsen
Jun 1, 1981·Journal of Clinical Gastroenterology·S BrozinskyA Ostrowitz

❮ Previous
Next ❯

Citations

Jun 9, 1989·The American Journal of Medicine·S K Lam
Jan 1, 1996·Scandinavian Journal of Gastroenterology. Supplement·K Lauritsen, E Christensen
Jan 1, 1988·Scandinavian Journal of Gastroenterology. Supplement·G Bodemar
Jan 1, 1989·Scandinavian Journal of Gastroenterology. Supplement·P RampalF Prunieras
Feb 20, 2018·Journal of Neurosciences in Rural Practice·Deepika DhimanRajiv Raina
Jan 1, 1987·Alimentary Pharmacology & Therapeutics·F Halter, F Eigenmann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.