Symptomatic Tetralogy of Fallot in Young Infants: Primary Repair or Shunt-Pediatric Health Information System Database Analysis

World Journal for Pediatric & Congenital Heart Surgery
Karthik V RamakrishnanPranava Sinha

Abstract

Compare the early outcomes and hospital charges of early primary repair and systemic-to-pulmonary artery shunt for neonates and young infants (≤90 days of age) with tetralogy of Fallot using data from the Pediatric Health Information System database. The Pediatric Health Information System database was queried for patients <90 days of age with primary diagnosis of tetralogy of Fallot who underwent nonelective surgical repair or palliation between January 2008 and December 2014. The initial cohort of 821 patients (group 1 early primary repair, N = 554; group 2 systemic-to-pulmonary artery shunt, N = 267) was propensity score matched (248 patients in each group) to account for baseline imbalances in age and prostaglandin use. Comparison of unmatched groups revealed younger age and higher incidence of extracardiac anomalies ( P = .02) and prematurity ( P = .04) in group 2. Mortality was comparable between the groups (group 1: 20 [4%] of 554 vs group 2: 11 [4%] of 267, P = .74). Irrespective of the type of procedure, prematurity (odds ratio [OR] = 3.3, 95% confidence interval [CI]: 1.5-7.4) and extracardiac anomalies (OR = 2.5, 95% CI: 1.2-5.3) were independent risk factors for mortality. Propensity score-matched analysis revealed ...Continue Reading

References

May 1, 1990·The Annals of Thoracic Surgery·D TamisierJ Y Neveux
May 21, 2008·Interactive Cardiovascular and Thoracic Surgery·Hunaid A VohraMarcus P Haw
Aug 25, 2010·The Annals of Thoracic Surgery·Hamad F Al HabibMarshall L Jacobs
Mar 17, 2012·Journal of the American College of Surgeons·Colleen G KochJ Michael Henderson
Mar 16, 2013·Journal of Vascular Surgery·Rodney P BensleyMarc L Schermerhorn
Jul 25, 2013·The Journal of Thoracic and Cardiovascular Surgery·Matthew B SteinerParthak Prodhan
Dec 3, 2014·The Annals of Thoracic Surgery·Syed Murfad PeerPranava Sinha
Nov 7, 2015·The Annals of Thoracic Surgery·George M HoffmanKathleen A Mussatto
May 8, 2016·The Annals of Thoracic Surgery·Michael E A CunninghamPranava Sinha

❮ Previous
Next ❯

Citations

Aug 31, 2018·World Journal for Pediatric & Congenital Heart Surgery·Emile A Bacha
Aug 31, 2018·World Journal for Pediatric & Congenital Heart Surgery·Yves d'Udekem
Jan 7, 2020·Transboundary and Emerging Diseases·Y LiI D Robertson
Aug 11, 2020·Cardiology in the Young·Dasana LingaswamyRaman Krishna Kumar
Mar 18, 2021·The Journal of Thoracic and Cardiovascular Surgery·Athar M QureshiUNKNOWN Congenital Cardiac Research Collaborative Investigators
Jun 13, 2021·Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual·David J Barron, Anusha Jegatheeswaran
Apr 20, 2021·The Annals of Thoracic Surgery·Tara KaramlouRoosevelt G Bryant
Dec 24, 2019·The Annals of Thoracic Surgery·Tain-Yen Hsia

❮ Previous
Next ❯

Software Mentioned

Stata
nQuery Advisor

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.