Symptomatic vertebral hemangioma: treatment with radiotherapy

Journal of Cancer Research and Therapeutics
Ranen K AichPhalguni Gupta

Abstract

Vertebrae are the second commonest site among skeletal locations affected by hemangioma, but only about one per cent becomes symptomatic throughout the life. Though surgery, intra vertebral injection of various sclerosing agents have been tried in treating this benign process, no general consensus regarding management has been reached. Radiotherapy is emerging as a low cost, simple, non-invasive but very effective modality of treatment of symptomatic vertebral hemangioma. This study aims to find out the role of external beam radiotherapy in alleviating the symptoms of symptomatic vertebral hemangiomas without compromising the quality of life. Seven consecutive patients with symptomatic vertebral hemangioma were treated with a fixed dose of external beam radiotherapy; and muscle power was assessed before, after treatment and during follow-up. All patients showed improvement of muscle power, which increased with the passage of time. Pain relief with improvement of quality of life was obtained in all the patients. Effect of radiotherapy on vertebral hemangioma is dose-dependent and the dose limiting factor is the spinal cord tolerance. In the present era of IMRT, greater dose can be delivered to the parts of vertebra affected by t...Continue Reading

References

Mar 1, 1975·Brain : a Journal of Neurology·V L McAllisterJ W Bull
Jan 1, 1963·Acta Neurologica Scandinavica·A BergstrandH Lidvall

❮ Previous
Next ❯

Citations

Jan 12, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Didem UzunaslanTiraje Celkan
Aug 13, 2013·The Spine Journal : Official Journal of the North American Spine Society·Ying-jie HaoJia-zhen Li
Feb 28, 2015·Neurosurgical Review·Roberto TarantinoRoberto Delfini
Aug 2, 2016·Neurosurgical Focus·Viren S VasudevaMichael W Groff
Jan 12, 2019·Medicine·Kai YaoChongqi Tu
Sep 29, 2020·Seminars in Musculoskeletal Radiology·Roberto Luigi CazzatoAfshin Gangi
Nov 1, 2016·The American Journal of Case Reports·Mohammad AlfawarehZiad Audat
Jun 11, 2011·American Journal of Clinical Oncology·Leah H PortnowDaniel J Indelicato
Apr 12, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Marco V CorniolaEnrico Tessitore
Mar 2, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Yongye ChenNing Lang
Feb 19, 2021·Surgical Neurology International·Dimitrios PapadakosConstantine Constantoyannis
Oct 26, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Nathan Y YuJonathan B Ashman
Aug 27, 2021·British Journal of Neurosurgery·Krishnakumar KesavapisharadyEaswer Venkat Hariharan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.