PMID: 2100368Jan 1, 1990Paper

Symptoms and well-being during antihypertensive treatment with thiazide diuretics

Scandinavian Journal of Primary Health Care. Supplement
G Berglund

Abstract

Diuretic drugs seem to be well tolerated during long-term antihypertensive treatment. Although they induce severe side effects necessitating withdrawal more often than placebo, the frequency of such withdrawals seem to be equal to that induced by beta-blocker treatment. The subjective tolerability as judged by questionnaires for symptoms and well being scores seems to indicate an over-all small improvement in patient well being. The effects in this respect seem to be similar to those exerted by a selective beta-blocker.

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