Symptoms in patients with giardiasis undergoing upper gastrointestinal endoscopy

Endoscopy
G Oberhuber, M Stolte

Abstract

The aim of the study was to compare symptoms of Giardia-positive and -negative patients undergoing upper gastrointestinal endoscopy. Multi-center questionnaire-based case-control study of 120 Giardia-positive and -negative patients who underwent upper endoscopy. Cases were identified through histological detection of trophozoites of Giardia lamblia in duodenal biopsy specimens. Giardia-negative patients with inconspicuous duodenal histology served as controls. There was a clear male predominance in the Giardia-positive groups, with 75 cases (62.5 %) being male and 45 (37.5 %) female (P < 0.0001). Giardia-positive cases tended to be older than controls (median 60 years vs. 45.2 years, P < 0.009). The main symptom of positive cases were tenderness to palpation (52.1%), abdominal discomfort (43.3 %), sensation of fullness (40.8%), distension (37.5%), epigastralgia (37.5%), nausea and/or vomiting (35.8%), heartburn (26.7%), and diarrhea (25.8%). Only sensation of fullness (P < 0.02), nausea/vomiting (P < 0.02) and heartburn (P < 0.03) were observed significantly more often in positive cases. Foul-smelling stools, considered typical for giardiasis, were observed in 5.8% of cases. Symptoms lasted for less than 1 month in 28.2 % of ca...Continue Reading

Citations

Jun 18, 2003·Journal of Clinical Gastroenterology·Michal KoriRam Reifen
Jul 9, 2008·Scandinavian Journal of Gastroenterology·Thean S ChewDavid S Sanders
Dec 1, 2001·Gastrointestinal Endoscopy·G M EisenUNKNOWN American Society for Gastrointestinal Endoscopy
Mar 30, 2010·Gastrointestinal Endoscopy·Bo ShenJason A Dominitz
Oct 30, 2007·The Journal of Infection·Kurt HanevikNina Langeland
Oct 22, 2011·The American Journal of Medicine·Paul T CanteyMichael J Beach
Aug 29, 2019·Current Pharmaceutical Biotechnology·Aref ShariatiTaher Azimi
Apr 30, 2017·Tissue Barriers·Thibault AllainAndré G Buret
Jul 8, 2019·Trends in Parasitology·Thibault AllainAndre G Buret

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