PMID: 3748473Jul 1, 1986Paper

Synaptic actions of cutaneous A delta and C fibers on primate hindlimb alpha-motoneurons

Neuroscience Research
Y HoriW D Willis

Abstract

Postsynaptic potentials evoked in hindlimb alpha-motoneurons by stimulation of a cutaneous nerve (sural) with finely graded stimulus strengths were analyzed in the primate, monitoring the spinal cord potentials and afferent nerve volleys in the sural nerve. It was observed that activities in A alpha beta, A delta and C fibers of the cutaneous nerve elicited characteristic excitatory and/or inhibitory postsynaptic potentials (EPSPs and/or IPSPs) with different latencies and durations in extensor and flexor motoneurons. Volleys in A delta fibers of the cutaneous nerve produced EPSPs in 57% of flexor and 31% of extensor motoneurons tested, whereas IPSPs were produced by A delta volleys in 41% of flexor and 62% of extensor motoneurons. EPSPs with longer latencies and longer durations were evoked by cutaneous C fiber volleys in 55% of flexor and 34% of extensor motoneurons, whereas IPSPs due to C volleys were recorded in 9% of flexor and 14% of extensor motoneurons. A alpha beta and A delta volleys caused motoneurons to fire in several instances, and some motoneurons discharged repetitively during the depolarizations evoked by activities in C fibers of the nerve. Central latency for transmission in interneuronal chains in the spinal...Continue Reading

References

Oct 13, 1978·Experimental Brain Research·G VialaP Buser
Oct 1, 1978·Experimental Neurology·G A IwamotoI H Wagman
Aug 8, 1977·Experimental Brain Research·K KandaB Walmsley
Mar 1, 1974·Journal of Neurophysiology·W D WillisR A Maunz
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May 7, 1984·Brain Research·Y HoriW D Willis
Feb 24, 1984·Neuroscience Letters·K EndoW D Willis
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Jan 1, 1964·Acta Physiologica Scandinavica. Supplementum·C J CLEMEDSON, A JOENSSON

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