PMID: 6402603Feb 1, 1983Paper

Synaptic membrane domains in photoreceptors of chick retina: a thin-section and a freeze-fracture study

Journal of Ultrastructure Research
N G CooperL G Boykins

Abstract

In this freeze-fracture study of synaptic terminals of chick photoreceptors, three regions of synaptic terminal plasmalemma can be distinguished on the basis of intramembrane characteristics. The first region is the synaptic vesicle fusion region in which rows of P-face depressions and E-face mounds are observed. In the absence of exocytotic figures this zone is relatively free of P-face particles and E-face pits. Adjacent to this, a second region is seen, rich in P-face particles and complementary E-face pits. This second region waxes and wanes in size during dark and light stimulation (Cooper and McLaughlin, 1982) and may correspond to similar expansions and contractions of synaptic plasmalemma induced by less physiological modes of stimulation, as observed in other synaptic terminals (Ceccarelli et al., 1979b; Model et al., 1975; Boyne and McLeod, 1979). During the waxing period, P-face particles and E-face pits are present in this membrane, and its expansion gives rise to diverticula of the synaptic terminal. During the waning period when the diverticula begin to disappear, aggregates of P-face particles and complementary patches of E-face pits are seen in the diverticular membrane. The third region, the nonsynaptic plasmal...Continue Reading

Citations

Sep 8, 1989·The Journal of Comparative Neurology·E Gleason, M Wilson
Jan 1, 1989·Neuroscience Research. Supplement : the Official Journal of the Japan Neuroscience Society·J Usukura
Dec 10, 1984·The Journal of Comparative Neurology·N G Cooper, B J McLaughlin
Jul 8, 1986·The Journal of Comparative Neurology·D A Steindler, N G Cooper

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.