PMID: 6109006Nov 1, 1980Paper

Synaptic proteins after electroconvulsive seizures in immature rats

Journal of Neurochemistry
O S JørgensenC G Wasterlain

Abstract

The forebrain content of several rat brain synaptic proteins (synaptin, D1, D2, and D3) was reduced in rats receiving electroconvulsive seizures on days 2-11, 9-18, or 19-28 and sacrificed at the age of 30 days. Forebrain weight, total protein, and the glial enzyme glutamine synthetase were also decreased, whereas the neuronal enolase 14-3-2 was unchanged. The findings suggest that seizures in the immature rat brain resulted in a parallel reduction of synaptic material and of the amount of glial cells. The increased concentration of the enolase 14-3-2 found in rats seizured on days 19-28 may reflect the high demands on the glycolytic system during the seizures.

References

Mar 25, 1977·Science·A Martinez-HernandezM D Norenberg
Jan 1, 1978·Journal of Neurochemistry·E Bock
Aug 17, 1979·Science·O S Jorgensen, T G Bolwig
Oct 1, 1974·Journal of Neurochemistry·O S Jorgensen, E Bock
Jul 1, 1973·Archives of Neurology·C G Wasterlain, F Plum
Oct 1, 1973·Developmental Medicine and Child Neurology·E Schiottz-Christensen, P Bruhn
Jan 1, 1973·Scandinavian Journal of Immunology. Supplement·B Weeke
Aug 4, 1980·Brain Research·O S Jørgensen, M Møller

❮ Previous
Next ❯

Citations

Jan 1, 1982·Journal of Neural Transmission·O S JørgensenK Jellinger
Feb 1, 1993·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M J LitzingerJ R Abbott
Jan 1, 1993·Epilepsia·C G WasterlainR Sankar
Jul 1, 1994·Brain & Development·C G Wasterlain, Y Shirasaka
Dec 1, 1982·Experimental Neurology·B E Dwyer, C G Wasterlain
Jul 28, 2004·Pediatric Clinics of North America·Mary L Zupanc
Dec 20, 2018·Epilepsia Open·Kerry W ThompsonClaude G Wasterlain

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.