PMID: 6969297Jun 1, 1980Paper

Synaptogenesis in the vestibular sensory epithelium of the chick embryo

Journal of Neurocytology
R D Ginzberg, N B Gilula

Abstract

The formation of synapses between sensory cells and the terminals of afferent axons has been examined in the embryonic chick labyrinth. Neurites initially cross the otocyst basal lamina and ramify among the undifferentiated epithelial cells by stage 25 Hamburger and Hamilton. At the same time granular vesicles, with diameters averaging 130nm, appear in the basal cytoplasm of a few of the epithelial cells. These vesicles often exist in groups at sites contact with; neurites. By stages 27-28, non membrane-bound densities are frequently found in association with groups of granular vesicles at the plasma membrane. Smaller, clear synaptic vesicles are also a prominent component of these arrangements in presumptive hair cells. Presynaptic ribbons opposite postsynaptic densites are identifiable at about stage 28, and their number increases during subsequent embryonic stages. Specialized appositions, including adherent, postsynaptic and possibly gap junctional contacts, join epithelial cells and nerve terminals throughout this period. The distribution of these junctions is variable, and is not necessarily correlated with the sites of formation of presynaptic ribbons. By stage 32, well-developed chemical synapses consisting of presynapt...Continue Reading

References

Mar 1, 1978·Otolaryngology·T R Van De WaterH Nordeman
Jun 27, 1977·Experimental Brain Research·R Klinke, E F Evans
Oct 24, 1977·Experimental Brain Research·R Klinke, W Oertel
Oct 24, 1977·Experimental Brain Research·R Klinke, W Oertel
Jun 1, 1978·Journal of Neurocytology·N Hirokawa
Dec 1, 1976·The Journal of Comparative Neurology·B J McLaughlin
Jan 1, 1970·Zeitschrift für Zellforschung und mikroskopische Anatomie·D G Jones, E Revell
Apr 1, 1971·Journal of Ultrastructure Research·T Takasaka, C A Smith
Nov 1, 1971·The Journal of General Physiology·A B Steinbach, M V Bennett
Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·V LoprestiC Levinthal
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·G H Vázquez-Nin, J R Sotelo
Apr 1, 1968·Journal of Ultrastructure Research·D W Hamilton
Jan 1, 1970·Zeitschrift für Zellforschung und mikroskopische Anatomie·D G Jones, E Revell
Nov 1, 1967·The American Journal of Anatomy·T L Lentz
Jul 1, 1969·The Journal of Cell Biology·A M Kelly, S I Zacks
Jan 1, 1951·Journal of Morphology·V HAMBURGER, H L HAMILTON

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Citations

Dec 1, 1986·Journal of Neurocytology·H M SobkowiczC V Levenick
Jan 1, 1984·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M D Ard, D K Morest
Jan 1, 1988·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·K D PeusnerP F Mansfield
Oct 31, 1998·Brain Research. Brain Research Reviews·M D Ross, D L Tomko
Feb 5, 2004·Hearing Research·J David DickmanMelissa Lowe
Jan 25, 2014·Hearing Research·Andrea C BattistiDonna M Fekete
Jul 28, 2015·Gene Expression Patterns : GEP·Kristi NguyenJennifer M Jones
Jul 23, 2013·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Ying-Jie SunAkira Naito
Jun 23, 2005·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Sergio MasettoPaolo Valli
Jan 1, 1985·Acta Oto-laryngologica. Supplementum·A Sans, C Dechesne
Jan 1, 1984·The Annals of Otology, Rhinology, and Laryngology·D Bagger-Sjöbäck, M Anniko
Jun 20, 2003·The Journal of Comparative Neurology·Elizabeth C OesterleEdwin W Rubel
Jan 24, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Andrea C Battisti, Donna M Fekete
Dec 7, 2018·The Journal of Comparative Neurology·M Katie ScottDonna M Fekete
Feb 16, 2010·Developmental Neurobiology·David HussJ David Dickman
Dec 22, 1991·The Journal of Comparative Neurology·S BartolamiG Richardson
Dec 1, 1986·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·E HornB Rayer
Dec 17, 1990·Brain Research·D AcuñaG Meza
Aug 22, 1989·The Journal of Comparative Neurology·C S von Bartheld, E W Rubel
Oct 22, 1989·The Journal of Comparative Neurology·J T Corwin, D A Cotanche
Jan 2, 1995·The Journal of Comparative Neurology·R GoodyearG Richardson

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