Synaptotagmin gene content of the sequenced genomes

BMC Genomics
Molly Craxton

Abstract

Synaptotagmins exist as a large gene family in mammals. There is much interest in the function of certain family members which act crucially in the regulated synaptic vesicle exocytosis required for efficient neurotransmission. Knowledge of the functions of other family members is relatively poor and the presence of Synaptotagmin genes in plants indicates a role for the family as a whole which is wider than neurotransmission. Identification of the Synaptotagmin genes within completely sequenced genomes can provide the entire Synaptotagmin gene complement of each sequenced organism. Defining the detailed structures of all the Synaptotagmin genes and their encoded products can provide a useful resource for functional studies and a deeper understanding of the evolution of the gene family. The current rapid increase in the number of sequenced genomes from different branches of the tree of life, together with the public deposition of evolutionarily diverse transcript sequences make such studies worthwhile. I have compiled a detailed list of the Synaptotagmin genes of Caenorhabditis, Anopheles, Drosophila, Ciona, Danio, Fugu, Mus, Homo, Arabidopsis and Oryza by examining genomic and transcript sequences from public sequence databases...Continue Reading

References

Nov 25, 1988·Nucleic Acids Research·F Corpet
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·A W Hudson, M J Birnbaum
Mar 20, 1995·FEBS Letters·M Craxton, M Goedert
Jan 1, 1994·Methods in Molecular Biology·W R Pearson
Aug 16, 1994·Proceedings of the National Academy of Sciences of the United States of America·B S Hilbush, J I Morgan
Jun 1, 1996·Molecular Biotechnology·R Staden
Mar 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·J M BabityH A Robertson
May 15, 1985·Physical Review. B, Condensed Matter·P H HannahP T Andrews
Feb 15, 2001·The Biochemical Journal·M Fukuda, K Mikoshiba
Feb 24, 2001·European Journal of Cell Biology·C von Poser, T C Südhof
Sep 7, 2001·Genomics·M Craxton
Dec 12, 2001·The Journal of Biological Chemistry·Thomas C Südhof
Apr 12, 2002·Developmental Biology·You KatsuyamaYasushi Okamura
Jun 6, 2002·The Biochemical Journal·Ward C Tucker, Edwin R Chapman
Jun 6, 2003·Biochemical and Biophysical Research Communications·Mitsunori Fukuda
Aug 9, 2003·Science·Barry HoopengardnerRobert Reenan
Oct 16, 2003·Biochemical and Biophysical Research Communications·C BagaláT Maciag
Apr 2, 2004·Journal of Neurochemistry·Arash NakhostWayne S Sossin
May 5, 2004·Genome Research·James StalkerAntony V Cox

❮ Previous
Next ❯

Citations

Aug 25, 2005·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Jicheng ZhangChunguang Zhang
Jul 5, 2006·Cell and Tissue Research·Ute Becherer, Jens Rettig
Jan 22, 2010·Protoplasma·Till IschebeckIngo Heilmann
Aug 4, 2010·Proceedings of the National Academy of Sciences of the United States of America·Motojiro YoshiharaJ Troy Littleton
Jun 17, 2010·The Journal of Biological Chemistry·Jimena Castillo BennettLuis S Mayorga
Aug 7, 2010·The Journal of Biological Chemistry·Zhao Wang, Edwin R Chapman
May 30, 2008·The Journal of Biological Chemistry·Akhil BhallaEdwin R Chapman
Mar 9, 2012·Molecular Biology of the Cell·Camin DeanEdwin R Chapman
Feb 18, 2009·Molecular Biology and Evolution·Jianning LvYongfeng Jin
Jul 30, 2010·Cold Spring Harbor Perspectives in Biology·Hannah V McCueRobert D Burgoyne
Dec 18, 2008·The Plant Cell·Nancy A Eckardt
Sep 2, 2006·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Miguel MontesJ Justin Robert
Nov 23, 2006·BMC Neuroscience·Guy BrachyaMichal Linial
Mar 20, 2014·International Journal of Molecular Sciences·Gian-Pietro Di SansebastianoLaura Arru
Mar 25, 2014·Nature Neuroscience·Huisheng LiuEdwin R Chapman
Mar 29, 2005·Proceedings of the National Academy of Sciences of the United States of America·Enfu HuiEdwin R Chapman
Mar 8, 2005·Trends in Plant Science·Frantisek BaluskaDiedrik Menzel
Apr 19, 2006·The Journal of Cell Biology·Malika AhrasSharon A Tooze
Feb 23, 2010·Biochemical and Biophysical Research Communications·Charu LataManoj Prasad
Nov 22, 2014·Frontiers in Plant Science·Asako UchiyamaSondra G Lazarowitz
May 30, 2008·Journal of Molecular Biology·Emma ConnellBazbek Davletov
Oct 22, 2015·Biological Reviews of the Cambridge Philosophical Society·Helmut Plattner
Aug 10, 2007·Biochemical and Biophysical Research Communications·Dan ZhuTao Xu
Feb 27, 2007·Molecular and Cellular Neurosciences·Eleanor A MathewsJames B Rand
Apr 2, 2017·Biochimica Et Biophysica Acta. Molecular Cell Research·Yasunori Saheki, Pietro De Camilli
Oct 1, 2004·The Journal of Biological Chemistry·Mitsunori FukudaAkitsugu Yamamoto
Apr 3, 2007·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Takashi Tsuboi, Mitsunori Fukuda
Aug 2, 2007·The European Journal of Neuroscience·Ivan ManziniWolfgang Rössler
Dec 7, 2007·Journal of Neuroscience Research·Eiko Kanno, Mitsunori Fukuda
Nov 26, 2008·The Journal of Comparative Neurology·Tobias MittelsteadtSusanne Schoch

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

Spin
Ensembl
Align
clustalw
Cladogram

Related Concepts

Related Feeds

Alternative splicing

Alternative splicing a regulated gene expression process that allows a single genetic sequence to code for multiple proteins. Here is that latest research.