PMID: 5908074Feb 11, 1966

Synchronization of mammalian cells with tritiated thymidine

Science
G F Whitmore, S Gulyas

Abstract

Short exposures of mammalian cells to tritiated thymidine of high specific activity destroys the proliferative capacity of mammalian cells. Since the killing is limited to cells that have synthesized DNA in the presence of the labeled compound, an exposure duration of less than one generation can yield a synchronized population.

Citations

Jan 1, 1971·In Vitro·G F Whitmore
Aug 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·G Sauer, V Defendi
Jun 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·L H ThompsonG F Whitmore
Apr 1, 1969·The Journal of Cell Biology·R Bischoff, H Holtzer
Jul 1, 1971·Cell and Tissue Kinetics·A H Nias, M Fox
Mar 1, 1977·Cell and Tissue Kinetics·P SchmialekB Zapf
Feb 23, 1973·Biochimica Et Biophysica Acta·J Hatzfeld
Aug 1, 1973·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·A M Rauth, M Domon
May 1, 1978·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·T D GriffithsD B Dahle
Sep 27, 2012·DNA Repair·L H Thompson
Nov 1, 1966·Experimental Cell Research·J H Kim, B K Stambuk
Jul 1, 1979·The Journal of Surgical Research·W J PetersK Iwano
Jul 1, 1987·Cell and Tissue Kinetics·D M Easton, M H Schneiderman
Feb 1, 1971·Experimental Cell Research·C J Bostock, D M Prescott
Jan 14, 1967·Nature·S E Pfeiffer, L J Tolmach
Nov 1, 1989·International Journal of Radiation Biology·G F WhitmoreS Gulyas
Jan 1, 1969·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·L H Thompson, R M Humphrey
Apr 1, 1977·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·D G Stetka, P L Webster
Jun 1, 1972·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·B Cullen

Related Concepts

Cell Division Phases
DNA, Double-Stranded
L Cells (Cell Line)
Thymidine
Tritium
Culture Techniques

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