Synchronous diffuse ganglioneuromatosis and multiple schwannomas of the colon: A case report and literature review

Experimental and Therapeutic Medicine
Changli LuHong Bu


Diffuse ganglioneuromatosis (DG) of the gastrointestinal tract is a rare condition that is closely associated with neurofibromatosis type 1 and multiple endocrine neoplasia type 2B. The occurrence of DG with multiple schwannomas, which, of the GI tract, usually affect the stomach, is considerably more rare. The present study describes the case of a 54-year-old male with indolent DG, principally involving the small intestine and colon, associated with multiple schwannomas in the subserosa. The patient was treated with surgery. A brief overview of intestinal ganglioneuromatous lesions and the associated conditions is additionally presented.


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Apr 2, 2014·Gastroenterology Research and Practice·Lijun ZhengJiafu Ji

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