Synchronous polypectomy during endoscopic diagnosis of colorectal cancer - is the risk of tumour implantation at the polypectomy site significant?

BMC Gastroenterology
W J TanM H Chew

Abstract

Synchronous polypectomy in colonic malignancies is contentious due to the perceived risks of tumour implantation at polypectomy sites (PS). We assess the risks of tumour implantation after synchronous polypectomy. An analysis of all endoscopies for cancer that were accompanied by synchronous polypectomies from 2005 to 2009 was performed. The incidence of metachronous colorectal cancers located at the same segment of a previous PS was the surrogate for tumour implantation. Data on patient demographics, tumour and polyp location(s) and follow-up outcomes were extracted. The rate of metachronous lesions at the same segment of a previous PS between patients who had all synchronous PS resected (Group A) and patients with PS left in-situ (Group B) were compared. Two hundred and eighty-four patients had synchronous polypectomy performed during their initial endoscopy for cancer. Three patients were lost to follow-up and, in the remaining 281 patients, 87 (31.0%) were in Group A while 194 (69%) were in Group B. Median age, gender, tumour location, tumour stage, and pathological characteristics were similar between both groups. 2 (0.7%) patients developed local recurrences. Six (2.1%) patients developed metachronous lesions, four of whi...Continue Reading

References

Dec 1, 1992·The British Journal of Surgery·E BrulletJ M Bordas
Jun 1, 1968·Archives of Surgery·S K Yu, I Cohn
Mar 1, 1984·American Journal of Surgery·J M Langevin, S Nivatvongs
Nov 1, 1980·Diseases of the Colon and Rectum·F J Burns
Jan 1, 1997·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·A TsunodaM Kusano
Apr 20, 2001·Journal of the National Cancer Institute·H NelsonUNKNOWN National Cancer Institute Expert Panel
Sep 11, 2002·Gut·J H ScholefieldUNKNOWN Association of Coloproctology for Great Britain and Ireland
Apr 25, 2006·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·I J ParkJ C Kim
Mar 14, 2007·International Journal of Cancer. Journal International Du Cancer·Alexandre Loktionov
Aug 19, 2007·World Journal of Gastroenterology : WJG·Min Sun Kim, Young Jin Park
Feb 26, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A R G Sheel, D Y Artioukh
Apr 29, 2015·International Journal of Cancer. Journal International Du Cancer·Anne-Marie BouvierValérie Jooste

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Methods Mentioned

BETA
biopsy
surgical resection
biopsies

Software Mentioned

SPSS

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