Synchronous tumors: adenosquamous carcinoma of pancreas and GIST of stomach.

Journal of Gastrointestinal Cancer
Constantin A DasanuGuru Trikudanathan

Abstract

We report herein a unique case of an adenosquamous carcinoma (ASC) of the pancreas and a synchronous gastrointestinal stromal tumor (GIST) of stomach in a 75-year-old Caucasian male. He presented with painless jaundice and generalized pruritus and was found to have a pancreatic head mass. Whipple's procedure was performed and yielded the above diagnoses. Ductal pancreatic adenocarcinoma, not a much rarer and more aggressive ASC subtype, has previously been shown to co-exist with GIST in some surgical series. In addition, the incidentally discovered GIST in our patient involved the stomach and not the small intestine, which is the predominant GIST location when concurrently diagnosed with other GI tumors. At the time of this publication, our patient, who received adjuvant chemoradiotherapy, remains disease-free 14 months after the abdominal surgery.

References

May 16, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·D E KardonC S Heffess
Sep 19, 2006·World Journal of Gastroenterology : WJG·Marek WronskiIreneusz W Krasnodebski
Aug 19, 2007·Journal of Gastroenterology·Łukasz LiszkaJoanna Huszno
Apr 2, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Guido BiascoUNKNOWN GIST Study Group, Bologna University
Apr 29, 2009·World Journal of Gastroenterology : WJG·Yan-Jun LiuXiao-Ting Wu

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Citations

Oct 2, 2019·Journal of Research on Adolescence : the Official Journal of the Society for Research on Adolescence·Megan DuvenageKathryn L Modecki
Aug 23, 2019·World Journal of Gastroenterology : WJG·Johanna WaidhauserBruno Märkl

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