PMID: 98459Apr 1, 1978Paper

Syndrome of multiple mucosal neurofibromas, pheochromocytoma and medullary thryoid carcinoma. Report of a case

International Journal of Oral Surgery
G Anneroth, A Heimdahl

Abstract

The present article reports a case of multiple endocrine neoplasia (MEN) syndrome, type IIb, including the following components: pheochromocytoma, medullary thyroid carcinoma, hyperplastic corneal nerves and multiple mucosal oral and ocular neurofibromas. The patients, a 35-year-old male also exhibited a series of other pertinent findings, i.e. thickened eyelids, marfanoid habitus and widened mandibular canal and mental foramina. In the discussion the clinical and histopathologic characteristics of the present case are compared with similar findings in other previously published cases. The multiple oral mucosal neurofibromas are described clinically and histopathologically and are stated as a pathognomonic early sign of the syndrome.

References

Jun 1, 1976·Oral Surgery, Oral Medicine, and Oral Pathology·J A CarneyS A Lovestedt
Dec 1, 1974·Archives of Internal Medicine·A D Marks, B J Channick
Aug 1, 1973·The Journal of Clinical Endocrinology and Metabolism·E F VoelkelR J Wurtman
Jan 1, 1966·The Journal of Pathology and Bacteriology·E D Williams, D J Pollock
Jan 1, 1971·Hormones·C R Heard, R J Stewart
Feb 1, 1971·Oral Surgery, Oral Medicine, and Oral Pathology·R C BartlettP Mandelstam
Dec 1, 1970·Journal of Medical Genetics·H NankinJ Sapira
Sep 1, 1963·Oral Surgery, Oral Medicine, and Oral Pathology·G SHKLAR, I MEYER

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Citations

Jun 1, 1984·Irish Journal of Medical Science·G WalshM Slazenger
Dec 3, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Robert Bruce MacIntoshMichael Lee
Jan 7, 2010·The Angle Orthodontist·Brent AccursoCarl M Allen
May 1, 1995·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·C W HavemanR T Long

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