PMID: 3768214Oct 1, 1986Paper

Syndrome X: the haemodynamic significance of ST segment depression

British Heart Journal
R D LevyK M Fox

Abstract

The relation between chest pain, ST segment depression, and changes in left ventricular function was assessed in six patients with angina, a positive exercise test, and normal coronary arteries as assessed by arteriography (syndrome X). In the six patients with syndrome X and in six controls there was no significant rise in pulmonary artery diastolic pressure during treadmill exercise, although there was ST segment depression (range 1-4.5 mm) in the patients with syndrome X. In 19 patients with coronary artery disease, however, the pulmonary artery diastolic pressure increased by a median 5 mm Hg (range 0-13.6 mm Hg) on treadmill exercise. In only one patient with coronary artery disease, who showed 1 mm ST segment depression, was there no rise in pulmonary artery diastolic pressure. During ambulatory monitoring in patients with syndrome X there were 12 episodes of ST segment depression (greater than 1 mm) (4 painful, 8 painless) in which there was no change in pulmonary artery diastolic pressure. In the patients with coronary artery disease there were 29 episodes of angina during ambulatory monitoring and during all of them pulmonary artery diastolic pressure rose by a median 7.5 mm Hg (range 1.8-19.7 mm Hg). Unlike the haemod...Continue Reading

References

Jan 25, 1985·The American Journal of Cardiology·R O CannonS E Epstein
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Citations

Jun 1, 1994·International Journal of Cardiac Imaging·L LanzariniA Poli
Nov 15, 1991·Journal of the American College of Cardiology·P NihoyannopoulosA Maseri
Nov 15, 1996·Journal of the American College of Cardiology·G M RosanoP A Poole-Wilson
Aug 1, 1992·British Heart Journal·J S GibbsK M Fox
Jan 1, 1991·Postgraduate Medical Journal·M E Bourke, D L Patterson
Jun 1, 1988·The American Journal of Cardiology·R O Cannon, S E Epstein
Nov 1, 1990·Progress in Cardiovascular Diseases·J Chambers, C Bass
Mar 1, 1990·International Journal of Cardiology·R D Levy, K M Fox
Dec 1, 1991·American Heart Journal·T T Bashour
Apr 1, 1990·American Heart Journal·L SpinelliM Condorelli
Sep 1, 1987·The American Journal of Cardiology·E PicanoA L'Abbate
Mar 1, 1992·Circulation·R O CannonS E Epstein
Oct 1, 1989·Postgraduate Medicine·J L HoughtonM J Frank

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