PMID: 14044038Jul 1, 1963

SYNERGISM BETWEEN SULPHONAMIDE DRUGS AND ANTIBIOTICS OF THE POLYMYXIN GROUP AGAINST PROTEUS SP. IN VITRO

Journal of Clinical Pathology
F E RUSSELL

Abstract

Interesting synergism in vitro between a recently introduced antibiotic, colistin methane sulphonate, and sulphonamide drugs is described. The observations were extended to polymyxin B sulphate and sulphonamides with essentially similar results. The combinations are bactericidal at therapeutic levels, the ratio of drugs to one another is not critical, and the effect is present over a fairly wide pH range.

References

Jan 1, 1961·The Journal of Urology·G CARROLL, W F MALETTE
Jul 21, 1962·British Medical Journal·G TAYLOR, H ALLISON

Citations

Jul 1, 1977·Antimicrobial Agents and Chemotherapy·S ShimizuS Mitsuhashi
Apr 1, 1973·Antimicrobial Agents and Chemotherapy·J Z MontgomerieL B Guze
Jul 1, 1974·Antimicrobial Agents and Chemotherapy·J E Rosenblatt, P R Stewart
Feb 1, 1976·Antimicrobial Agents and Chemotherapy·F E ThomasR H Alford
Jun 1, 1975·Antimicrobial Agents and Chemotherapy·W H Traub, I Kleber
May 10, 1974·Annals of the New York Academy of Sciences·D S FeingoldI J Sud

Related Concepts

Totazina
Polymyxin M
Proteus
Sulfonamides

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