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Synergistic effects of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha: central monoamine, corticosterone, and behavioral variations

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology

May 2, 2000

K BrebnerHymie Anisman

Abstract

The proinflammatory cytokines interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha (TNF-alpha) influence neuroendocrine activity, promote central neurotransmitter alterations, and induce a constellation of symptoms collectively referred to as sickness behaviors. These cyt...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Interleukin-1
Interleukin-6
Ingestion
Mice, Inbred Strains
Anorexia
Anxiety Disorders
Psychosexual Disorders
Systemic Scleroderma
Behavior, Animal
1
80
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Synergistic effects of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha: central monoamine, corticosterone, and behavioral variations

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology

May 2, 2000

K BrebnerHymie Anisman

PMID: 10788757

DOI: 10.1016/s0893-133x(99)00166-9

Abstract

The proinflammatory cytokines interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor-alpha (TNF-alpha) influence neuroendocrine activity, promote central neurotransmitter alterations, and induce a constellation of symptoms collectively referred to as sickness behaviors. These cyt...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Interleukin-1
Interleukin-6
Ingestion
Mice, Inbred Strains
Anorexia
Anxiety Disorders
Psychosexual Disorders
Systemic Scleroderma
Behavior, Animal
1
80

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  • Citations91
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  • Citations91
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