Syntheses and structural characterization of dinuclear and tetranuclear iron(III) complexes with dinucleating ligands and their reactions with hydrogen peroxide

Inorganic Chemistry
L WesterheideS Schindler

Abstract

The iron(III) complexes [Fe(2)(HPTB)(mu-OH)(NO(3))(2)](NO(3))(2).CH(3)OH.2H(2)O (1), [Fe(2)(HPTB)(mu-OCH(3))(NO(3))(2)](NO(3))(2).4.5CH(3)OH (2), [Fe(2)(HPTB)(mu-OH)(OBz)(2)](ClO(4))(2).4.5H(2)O (3), [Fe(2)(N-EtOH-HPTB)(mu-OH)(NO(3))(2)](ClO(4))(NO(3)).3CH(3)OH.1.5H(2)O (4), [Fe(2)(5,6-Me(2)-HPTB)(mu-OH)(NO(3))(2)](ClO(4))(NO(3)).3.5CH(3)OH.C(2)H(5)OC(2)H(5).0.5H(2)O (5), and [Fe(4)(HPTB)(2)(mu-F)(2)(OH)(4)](ClO(4))(4).CH(3)CN.C(2)H(5)OC(2)H(5).H(2)O (6) were synthesized (HPTB = N,N,N',N'-tetrakis(2-benzimidazolylmethyl)-2-hydroxo-1,3-diaminopropane, N-EtOH-HPTB = N,N,N',N'-tetrakis(N' '-(2-hydroxoethyl)-2-benzimidazolylmethyl)-2-hydroxo-1,3-diaminopropane, 5,6-Me(2)-HPTB = N,N,N',N'-tetrakis(5,6-dimethyl-2-benzimidazolylmethyl)-2-hydroxo-1,3-diaminopropane). The molecular structures of 2-6 were established by single-crystal X-ray crystallography. Iron(II) complexes with ligands similar to the dinucleating ligands described herein have been used previously as model compounds for the dioxygen uptake at the active sites of non-heme iron enzymes. The same metastable (mu-peroxo)diiron(III) adducts were observed during these studies. They can be prepared by adding hydrogen peroxide to the iron(III) compounds 1-6. Using stopped-flow ...Continue Reading

References

Apr 5, 1991·Journal of Molecular Biology·M A HolmesR E Stenkamp
Jul 17, 1998·Current Opinion in Chemical Biology·S J Lange, L Que
Jul 2, 1999·Journal of Molecular Biology·J UppenbergG Andersson
Jul 30, 1999·Structure·L W GuddatJ L Martin
Apr 1, 2000·Current Opinion in Chemical Biology·L WesterheideB Krebs
Nov 7, 1996·Chemical Reviews·Bradley J. Wallar, John D. Lipscomb

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Citations

Jan 23, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Julia Bernhardette Hildegard StrautmannThorsten Glaser
Feb 22, 2013·Angewandte Chemie·Frédéric AvenierAlly Aukauloo
Nov 7, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Athanassios K BoudalisLawrence R Gahan
Nov 28, 2012·Angewandte Chemie·Tobias HoppeSiegfried Schindler
Nov 23, 2017·Angewandte Chemie·Adriana M MagherusanAidan R McDonald
Dec 7, 2010·Organic & Biomolecular Chemistry·Kaisa HelttunenMaija Nissinen
Jan 30, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Kazim R NaqviVictor Chechik
Nov 17, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Alexandre TrehouxFrédéric Avenier
Mar 16, 2021·Journal of Inorganic Biochemistry·Filitsa DimizaGeorge Psomas
Jun 9, 2005·Chemical Reviews·Sergey V KryatovSiegfried Schindler
Aug 22, 2018·Inorganic Chemistry·Nityananda DuttaManindranath Bera
Feb 12, 2004·Chemical Reviews·Anna L Gavrilova, Brice Bosnich
Feb 12, 2004·Chemical Reviews·Edit Y Tshuva, Stephen J Lippard

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