PMID: 9544942Apr 17, 1998Paper

Synthesis and activity of 3-epi-actinobolin

The Journal of Antibiotics
H AdachiT Takeuchi

Abstract

3-epi-Actinobolin was synthesized by the chemical transformation of actinobolin involving a key step of the reconstruction of fused delta-lacton skeleton via intramolecular acylation reaction. The analogue with low toxicity weakly inhibits Gram-positive and Gram-negative bacteria.

Citations

Feb 28, 2020·Journal of Natural Products·E Peter GreenbergMohammad R Seyedsayamdost
Apr 15, 2020·Journal of the American Chemical Society·Petra VojáčkováJakub Švenda

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