Synthesis and antibacterial activity of novel enolphosphate derivatives

Bioorganic Chemistry
Claude GrisonRaphael E Duval

Abstract

A new class of enolphosphates derivatives, the 1-alkenyldiphosphates, was designed and a rapid and efficient synthesis for these compounds was developed. These new molecules showed interesting in vitro antibacterial activities (MIC) against Gram-positive bacteria (Staphylococcus aureus) and Gram-negative pathogens including Pseudomonas aeruginosa and Escherichia coli.

Citations

Dec 30, 2014·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Kuruva Chandra SekharNaga Raju Chamarthi
Sep 29, 2015·Organic & Biomolecular Chemistry·William J KerrMuralikrishnan Rajamanickam

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