Synthesis and antimicrobial activity of new (E)-4-[piperidino (4'-methylpiperidino-, morpholino-) N-alkoxy]stilbenes

European Journal of Medicinal Chemistry
Elzbieta WyrzykiewiczBogdan Kedzia

Abstract

The synthesis of twenty-one new (E)-4-[piperidino-(4;-methylpiperidino-, morpholino-)N-alkoxy] stilbenes is reported. The compounds were tested for antimicrobial activities against Gram-negative, Gram-positive bacteria, and fungi. In particular, compounds 3b, 3c, 3f, 3g, 3h, 3k, 3l showed good antibacterial activity against Staphylococcus aureus and 3h, 3k, 3m, 3n also against Bacillus subtilis, as well as 3h, 3n also against Streptococcus faecalis.

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Citations

Jun 29, 2013·Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents·Hakan BektaşBahar Bilgin Sökmen
Jul 19, 2012·World Journal of Microbiology & Biotechnology·S Nishanth KumarC Mohandas
Feb 11, 2014·Journal of Enzyme Inhibition and Medicinal Chemistry·Łukasz PopiołekAnna Malm
Nov 20, 2013·Chemistry : a European Journal·Ramiz A BoulosScott G Stewart
Apr 22, 2017·Molecular Diversity·Zulfiqar Ali KhanSohail Anjum Shahzad
Jan 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Abdulmajeed S H Alsamarrai, Saba S Abdulghani
Mar 26, 2021·Advances in Pharmacological and Pharmaceutical Sciences·Zeleke DigafieRajalakshmanan Eswaramoorthy

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