PMID: 6105200Aug 1, 1980Paper

Synthesis and biological evaluation of p-bromospiperone as potential neuroleptic drug

Journal of Pharmaceutical Sciences
C C HuangH Y Meltzer

Abstract

p-Bromospiperone was prepared from the reaction of spiperone with bromine. It was tested for dopamine receptor binding affinity in vitro and its ability to stimulate prolactin secretion in vivo. The results indicate no significant change of biological activities due to the bromination of spiperone.

References


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Citations

Jan 1, 1986·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·B Maziere, C Loc'h
Jan 1, 1986·International Journal of Radiation Applications and Instrumentation. Part A, Applied Radiation and Isotopes·O T De Jesus, A M Friedman
Jan 1, 1982·International Journal of Nuclear Medicine and Biology·A M FriedmanM Cooper
Jan 1, 1986·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·C A OttoD M Wieland
Apr 1, 1986·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J C BaronY Agid
Nov 1, 1989·Biomedical & Environmental Mass Spectrometry·B DanieliL Zecca

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