Synthesis and catalytic activities of a Zn(ii) based metallomacrocycle and a metal-organic framework towards one-pot deacetalization-Knoevenagel tandem reactions under different strategies: a comparative study

Dalton Transactions : an International Journal of Inorganic Chemistry
Anirban KarmakarArmando J L Pombeiro

Abstract

Solvothermal reactions between a pyridine based amide functionalized dicarboxylic acid, 4,4'-{(pyridine-2,6-dicarbonyl)bis(azanediyl)}dibenzoic acid (H2L), and zinc(ii) nitrate in the absence and presence of a base produced the binuclear metallomacrocyclic compound [Zn2(L)2(H2O)4]·2(H2O)·6(DMF) (1) and the metallomacrocyclic based two dimensional MOF [Zn5(L)4(OH)2(H2O)4]n·8n(DMF)·4n(H2O) (2), respectively. Compound 1 bears two tetrahedral Zn(ii) centres, whereas the 2D framework 2 includes a penta-nuclear Zn(ii) cluster as a secondary building block unit, with two of the metal cations assuming a tetrahedral type geometry and the remaining three an octahedral type geometry. The topological analyses reveal that compound 1 has a 2-connected uninodal net and framework 2 has a 2, 8-connected binodal net. These compounds heterogeneously catalyse the tandem deacetalization-Knoevenagel condensation reactions carried out under conventional heating, microwave irradiation or ultrasonic irradiation. Comparative studies show that ultrasonic irradiation (final product yield of 99% after 2 h of reaction time) provides the most favourable method (e.g., microwave irradiation leads to a final product yield of 91% after 3 h of reaction time). Mor...Continue Reading

References

Feb 20, 2007·Dalton Transactions : an International Journal of Inorganic Chemistry·Lei YangRobert P Houser
Apr 19, 2008·Accounts of Chemical Research·Vivek Polshettiwar, Rajender S Varma
Jan 28, 2009·Acta Crystallographica. Section D, Biological Crystallography·Anthony L Spek
Sep 1, 2012·Chemical Communications : Chem Comm·Jinhee ParkHong-Cai Zhou
Apr 10, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Anirban KarmakarArmando J L Pombeiro
Aug 2, 2014·ChemSusChem·Amarajothi Dhakshinamoorthy, Hermenegildo Garcia
Jan 9, 2015·Acta Crystallographica. Section C, Structural Chemistry·George M Sheldrick
Feb 18, 2016·Chemical Society Reviews·Yan BaiHong-Cai Zhou
Aug 3, 2016·Chemical Communications : Chem Comm·Fengshou YuLicheng Sun
Sep 15, 2016·Chemical Reviews·Alexander SchoedelOmar M Yaghi
Nov 15, 2016·Chemical Society Reviews·Yuan-Biao HuangRong Cao
Jan 18, 2017·Chemical Reviews·Jiahui KouRajender S Varma
May 26, 2017·Chemical Reviews·Li ZhuLin-Bing Sun
Jun 3, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Liu YangZhong-Min Su
Jul 14, 2018·Chemical Society Reviews·Amarajothi DhakshinamoorthyHermenegildo Garcia
Apr 30, 2019·Chemical Society Reviews·Meili DingOmar M Yaghi

❮ Previous
Next ❯

Citations

Mar 7, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Anirban KarmakarArmando J L Pombeiro

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Software Mentioned

TOPOS
PLATON
/ SQUEEZE
Bruker SMART
SHELXS
SHELXL
WinGX System

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.