Synthesis and characterisation of dextran and pullulan sulphate

Carbohydrate Research
C MähnerE Nordmeier

Abstract

Dextrans and pullulans of different molar masses in the range of 10(4)-10(5) g/mol were sulphated via a SO3-pyridine complex. The degree of substitution achieved was DS = 2.4 and DS = 1.4 for dextran sulphate and DS = 2.0 and DS = 1.4 for pullulan sulphate, respectively. Confirmation of sulphation was given by FTIR spectroscopy. Asymmetrical S=O and symmetrical C-O-S stretching vibrations were detected at 1260 and 820 cm(-1). Reactivity of the polysaccharide C-atoms was determined by 13C NMR spectroscopy: For dextran this was C-3 > C-2 > C-4, while for pullulan it was C-6 > C-3 > C-2 > C-4.

Citations

Feb 1, 2003·International Journal of Biological Macromolecules·Jianhong YangTianyu Li
Jul 20, 2010·Biochemistry. Biokhimii︠a︡·F V VityazevYu S Ovodov
Jun 21, 2011·International Journal of Molecular Sciences·Hua ZhangZhi Zhang
Sep 16, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Ananda Marques de GodoiRosa Elisa Carvalho Linhares
Apr 15, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Yongqiang LiXiao Yu Wu
Nov 18, 2015·Carbohydrate Polymers·Ana Helena P GracherMarcello Iacomini
Feb 13, 2013·Carbohydrate Polymers·Jin GuDouglas D Archibald
Mar 21, 2013·International Journal of Biological Macromolecules·F T G S CardozoC M O Simões
Aug 2, 2006·Prikladnaia biokhimiia i mikrobiologiia·N M MestechkinaV D Shcherbukhin
Feb 12, 2019·Chemical Society Reviews·Hannah E CaputoMark W Grinstaff
Jul 1, 2010·Prikladnaia biokhimiia i mikrobiologiia·N M Mestechkina, V D Shcherbukhin
Jun 3, 2020·Nutrition and Cancer·Amira M Gamal-EldeenBassem M Raafat
Mar 18, 2021·Anais Da Academia Brasileira De Ciências·Weibing LanGuangzai Nong
Feb 13, 2013·Carbohydrate Polymers·Manish JindalAshok K Tiwary
Jun 24, 2009·Journal of Agricultural and Food Chemistry·Zahra AlahdadMahsa Majzoobi
Dec 17, 2009·Journal of Agricultural and Food Chemistry·Wei LiuLiangli Lucy Yu
Jun 29, 2021·Chemical Biology & Drug Design·Shiyu Huang, Gangliang Huang

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