Synthesis and characterization of bridged bis(amidato) rare earth metal amides and their applications in C-N bond formation reactions

Dalton Transactions : an International Journal of Inorganic Chemistry
Bei ZhaoYingming Yao

Abstract

Based on three bisamide proligands H2Ln (n = 1–3) (H2L1 = [(Me3C6H2CONHCH2)2CH2], H2L2 = [(Me3C6H2CONHCH2)2C(CH3)2], H2L3 = [Me3C6H2CONH(CH2)2]2NCH3), eight bis(amidato) trivalent rare-earth metal amides {LnRE[N(TMS)2]}2 (n = 1, RE = La (1), Sm (2), Nd (3), Y (4); n = 2, RE = La (5), Nd (6);n = 3, RE = La (7), Nd (8); TMS = SiMe3) were successfully synthesized by treatment of H2Ln with RE[N(TMS)2]3 in a 1 : 1 molar ratio. Complexes 3, and 5–8 were characterized by single-crystal X-ray diffraction, and NMR characterization was carried out for the La complexes 1, 5, 7 and the Y complex 4. These complexes exhibited high catalytic activities in both the direct amidation of aldehydes and the addition of amines with carbodiimine. It was found that the bis(amidato) rare earth metal amides bearing different linkers have different effects on the transformations and lanthanum and neodymium complexes performed better than others.

References

Sep 1, 1989·Journal of Medicinal Chemistry·A B ReitzB E Maryanoff
Jan 10, 2001·The Journal of Organic Chemistry·T J BakerM Goodman
Oct 10, 2006·Angewandte Chemie·Mark C WoodLaurel L Schafer
Dec 21, 2007·Organic Letters·SungYong Seo, Tobin J Marks
Jun 5, 2008·Chemistry : a European Journal·Kekeli Ekoue-Kovi, Christian Wolf
Dec 10, 2009·Journal of the American Chemical Society·David C LeitchLaurel L Schafer
Dec 9, 2010·Chemical & Pharmaceutical Bulletin·Tsutomu Ishikawa
May 5, 2011·Chemical Communications : Chem Comm·Xiao Fu, Choon-Hong Tan
Jan 12, 2012·Chemical Society Reviews·James E TaylorJonathan M J Williams
May 5, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Jaclyn A Thomson, Laurel L Schafer
Mar 6, 2013·Dalton Transactions : an International Journal of Inorganic Chemistry·Jing TuQi Shen
Mar 15, 2014·Chemical Society Reviews·Carlos Alonso-MorenoAntonio Otero
Oct 10, 2014·Chemical Communications : Chem Comm·Wen-Xiong ZhangZhenfeng Xi

❮ Previous
Next ❯

Citations

Apr 21, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Chao GongYingming Yao
Feb 2, 2017·Beilstein Journal of Organic Chemistry·Constantin MamatMartin Köckerling
Nov 23, 2019·Chemistry : a European Journal·Robert Kretschmer
May 20, 2021·Chemical Communications : Chem Comm·Shanmugam RevathiTapas Ghatak
Dec 10, 2016·The Journal of Organic Chemistry·Andrea Ojeda-Porras, Diego Gamba-Sánchez
Jan 18, 2018·The Journal of Organic Chemistry·Chengrong LuYingming Yao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.