Synthesis and cytotoxicity of a salicylihalamide A analogue

Journal of Natural Products
Shaoshan Tang, Karen L. Erickson

Abstract

The synthesis of a simple analogue of salicylihalamide A with a truncated lactone ring (+/- 2) was achieved in 10 steps. Its cytotoxicity profile in the NCI 60-cell-line human tumor assay differed significantly from that of salicylihalamide A in both level and specificity.

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Citations

Apr 2, 2015·Organic & Biomolecular Chemistry·Martin E Maier
Sep 12, 2012·Organic & Biomolecular Chemistry·Dan BalanMark A Rizzacasa
Nov 12, 2021·Chemical Communications : Chem Comm·James HarnedyLouis C Morrill

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