Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility

Organic & Biomolecular Chemistry
Tiddo J MooibroekA P Davis

Abstract

A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M(-1) are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.

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Citations

Oct 30, 2019·International Journal of Molecular Sciences·Flávia Costa Mendonça-NatividadeMaria Cristina Roque-Barreira
Aug 28, 2019·Chemistry : a European Journal·Antonio BauzáTiddo Jonathan Mooibroek
Nov 28, 2020·Journal of Molecular Graphics & Modelling·Rajesh KondabalaAmjad Ali
Oct 14, 2020·Chemistry : a European Journal·Hannah P Ferguson JohnsMarcey L Waters
May 9, 2021·Angewandte Chemie·Brian J J TimmerTiddo J Mooibroek
Jul 1, 2021·Chemical Communications : Chem Comm·Brian J J Timmer, Tiddo J Mooibroek
Feb 24, 2018·The Journal of Organic Chemistry·Hajime AbeMasahiko Inouye
May 9, 2018·The Journal of Organic Chemistry·Augustin LongAlexandre Martinez
Sep 7, 2021·Chemistry : a European Journal·Xander SchaapkensTiddo J Mooibroek

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