Synthesis and evaluation of protein-based biopolymer in production of silver nanoparticles as bioactive compound versus carbohydrates-based biopolymers

Royal Society Open Science
Altaf H BastaNayera A M Abdelwahed

Abstract

This overall process deals with evaluating the performance of silver nanoparticles, synthesized from sodium caseinate (SC) as green biological active agent, in comparison with widely produced from carboxymethyl cellulose, other carbohydrates (oxidized nanocellulose fibres (OC) and starch (St)). The TGA, FTIR and TEM, as well as its antimicrobial activities toward pathogenic Gram-positive and Gram-negative bacteria in addition to the yeast strain Candida albicans NRRL Y-477 were examined. In addition, with regard to their anti-tumour activity, the evaluation was studied via many cancer cell lines against RPE1 (normal retina cell line). The results revealed that the SC-Ag(I) and CMC-Ag(I) complexes were formed in six- and five-membered chelate rings, respectively, as nanoparticles, while linear chelation structure was formed in case of OC-Ag(I) and St-Ag(I) complexes. The complexation of SC with Ag(I) ions was recommended as promising stable and antimicrobial agent, with lower free Ag(I) ions and particle size than other Ag-complexes. Moreover, it provided anti-tumour activity of most tested cell lines (in vitro), with the following sequence HCT116 > PC3 > HePG 2 > MCF-7 > A549 with IC50 and IC90 values of 25.8 and 54.73 µg ml-1,...Continue Reading

Associated Datasets

References

Dec 24, 1997·The Journal of Pharmacy and Pharmacology·M I ThabrewI G McFarlane
May 26, 2004·Journal of Colloid and Interface Science·Ivan Sondi, Branka Salopek-Sondi
Dec 3, 2005·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Simone M de SouzaArtur Smânia
Mar 27, 2010·Current Pharmaceutical Design·Michael FrezzaQ Ping Dou
Aug 30, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Declan Gaynor, Darren M Griffith
Mar 28, 2013·Journal of Amino Acids·Giacomo PepePietro Campiglia
Sep 3, 2013·International Journal of Biological Macromolecules·Vijay Kumar ThakurRaju Kumar Gupta
Jan 3, 2016·Nanomedicine : Nanotechnology, Biology, and Medicine·Nelson DuránGerson Nakazato
Feb 12, 2017·International Journal of Nanomedicine·Andrea RónaváriMónika Kiricsi
Nov 7, 2017·European Journal of Medicinal Chemistry·Tamer NasrWafaa Zaghary
May 13, 2018·Materials Science & Engineering. C, Materials for Biological Applications·Mohammad OvesIqbal M I Ismail

❮ Previous
Next ❯

Citations

Jul 12, 2021·Environmental Research·M ManiK Kaviyarasu

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Related Papers

Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária
Fernanda Cristina Macedo RondonHilton César Rodrigues Magalhães
© 2021 Meta ULC. All rights reserved