PMID: 807523Aug 1, 1975

Synthesis and excretion of glycerol teichoic acid during growth of two streptococcal species

Infection and Immunity
R Joseph, G D Shockman

Abstract

Examination of both supernatant culture medium and cell pellets after exponential- and stationary-phase growth of Streptococcus mutans strain FA-1 and Streptococcus faecalis ATCC 9790 (S. faecium) showed the presence of [-3H]glycerol-labeled material that possessed several of the properties of glycerol teichoic acid. In the supernatant medium of S. mutans FA-1, an apparently large-molecular-size material, which eluted from agarose columns with the Kd value expected of a lipoteichoic acid, was observed. Large amounts of this material were present in supernatants during the stationary phase. In contrast, with S. faecalis only an apparently lower-molecular-weight form, with a Kd consistent with deacylated glycerol teichoic acid, was found in the growth medium. Both organisms had high-molecular-weight lipoteichoic acid in the cells along with the deacylated glycerol teichoic acid. The presence of relatively large amounts of glycerol teichoic acids in the medium was considered to be a result of excretion of these compounds rather than a result of cellular lysis.

Citations

Feb 7, 2002·Proceedings of the National Academy of Sciences of the United States of America·Lynn E Hancock, Michael S Gilmore
May 7, 1998·Microbiology and Immunology·K OhtaH Suginaka
Sep 1, 1977·Scandinavian Journal of Dental Research·J E CiardiJ A Reilly
Apr 20, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·David L HastyItzhak Ofek
Mar 1, 1980·Journal of Periodontal Research·R L O'GradyA J Wicken

Related Concepts

Acids
Antibodies, Bacterial
Cell-Free System
Paper Chromatography (Procedure)
Glycerin
Hydrolysis
Immune Sera
Streptococcus
Enterococcus faecalis
Teichoic Acids

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