Synthesis and Fluorescent Thermoresponsive Properties of Tetraphenylethylene-Labeled Methylcellulose.

Macromolecular Rapid Communications
Haoying WangJinping Zhou

Abstract

Functional polymer, especially the one based on renewable and sustainable materials, has attracted increasing attention to satisfy the growing demand for the design of stimuli-responsive devices. Methylcellulose (MC) is a water-soluble derivative of cellulose, which has been widely used in many fields for its biocompatibility and biological inertness. In this work, MC is labeled by tetraphenylethylene (TPE) via azide-alkyne click reaction to obtain a fluorescent cellulose-based derivative of MC-TPE. The degree of substitution of MC-TPE is determined to be 0.074, which can be self-assembled into micelles in water with the size of 42 ± 6 nm. MC-TPE shows thermoresponsivity and thermoreversibility in size, transmittance, and fluorescence, enabling it to work as a fluorescent thermosensor. Moreover, MC-TPE exhibits nontoxicity and biocompatibility, allowing its application in MCF-7 cell imaging. Therefore, this newly functional natural polymer shows promising potentials in the fields of sensing and bioimaging.

References

Sep 21, 2002·Chemical Communications : Chem Comm·J LuoB Z Tang
Apr 30, 2005·Angewandte Chemie·Dieter KlemmAndreas Bohn
Jun 22, 2006·Journal of the American Chemical Society·Sathya SrinivasachariTheresa M Reineke
Jul 11, 2007·Chemical Society Reviews·David FournierUlrich S Schubert
Jul 26, 2008·Nature Nanotechnology·Chang-Cheng YouVincent M Rotello
Jan 7, 2009·Journal of Pharmaceutical and Biomedical Analysis·Anant ParadkarPeter York
Dec 19, 2012·Journal of the American Chemical Society·Chris Wai Tung LeungBen Zhong Tang
May 15, 2013·Journal of the American Chemical Society·Zhengke WangBen Zhong Tang
May 23, 2014·ACS Applied Materials & Interfaces·Travis H JamesNicholas F Materer
Nov 18, 2015·Carbohydrate Polymers·Carol López de DicastilloMaria José Galotto
Jan 23, 2016·Chemical Reviews·Vinod K TiwariXi Chen
Jun 24, 2016·Nature Communications·Zhengke WangBen Zhong Tang
Mar 8, 2017·Macromolecular Rapid Communications·Meiying LiuXiaoyong Zhang
Oct 19, 2017·ACS Applied Materials & Interfaces·Duong Duc LaSheshanath V Bhosale
Mar 28, 2018·Critical Reviews in Food Science and Nutrition·Jian JuWeirong Yao
Dec 7, 2018·Macromolecular Rapid Communications·Wei HuangUwe H F Bunz
Nov 30, 2019·Journal of Hazardous Materials·Haq NawazJun Zhang
Mar 7, 2020·Macromolecular Rapid Communications·Céline CalvinoChristoph Weder
Mar 13, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Shuangyan WuEnjun Gao
Aug 21, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhengke WangBen Zhong Tang
Jul 7, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhengke WangBen Zhong Tang
Jul 11, 2020·Macromolecular Rapid Communications·Ting HanBen Zhong Tang
Jul 31, 2020·Macromolecular Rapid Communications·Xun HanChristopher N Bowman

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