Synthesis and in vitro antibacterial activity of cephalosporins with a pyridinium substituent carrying an isoxazole moiety at the C-3 position

Archives of Pharmacal Research
H ParkM Chang

Abstract

Several quaternary pyridinium cephalosporin analogues were prepared and evaluated in vitro for antibacterial activity against selected gram-positive and gram-negative organisms. Most of the synthesized analogues were either as effective or less effective against the tested bacterial organisms than the reference compounds, Cefpirome and Ceftazidime.

References

Oct 1, 1985·The Journal of Antimicrobial Chemotherapy·J C SteeleJ P Rissing
Feb 1, 1985·Antimicrobial Agents and Chemotherapy·R E KesslerF Leitner
Sep 1, 1980·The Journal of Antimicrobial Chemotherapy·E SchrinnerA Lutz
Jun 1, 1982·Antimicrobial Agents and Chemotherapy·H L Muytjens, J van der Ros-van de Repe
Sep 1, 1981·The Journal of Antimicrobial Chemotherapy·H C Neu

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Citations

May 13, 2004·Chemical Reviews·Sven MangelinckxNorbert De Kimpe

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