PMID: 8612041Jan 1, 1995Paper

Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine

Bioorganic & Medicinal Chemistry
C FabregaB Singer

Abstract

The preparation of synthetic oligodeoxynucleotides containing O4-benzylthymidine (Tbn) is described. The use of standard and t-butylphenoxyacetyl amino protecting groups is compared. The thermal stabilities of duplexes containing Tbn paired with adenine and guanine have been measured.

References

Oct 10, 1986·Nucleic Acids Research·T R Webb, M D Matteucci
Jan 1, 1982·Annual Review of Biochemistry·B Singer, J T Kuśmierek
Feb 25, 1994·Nucleic Acids Research·N N PolushinJ S Cohen
May 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M K DosanjhB Singer

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Citations

Jan 22, 2008·Chemistry & Biodiversity·Stefania MazziniRamon Eritja
Aug 2, 2012·Organic & Biomolecular Chemistry·Francis P McManusChristopher J Wilds

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