journal cover

Synthesis, characterization and anticonvulsant activity of new series of N-modified analogues of VV-hemorphin-5 with aminophosphonate moiety

Amino Acids

Nov 1, 2019

Petar T TodorovNadezhda Todorova

Get paper from

Abstract

A new series of N-modified analogues of the VV-hemorphin-5 with aminophosphonate moiety have been synthesized, characterized and investigated for anticonvulsant activity. The novel peptide analogues were prepared by solid-phase peptide synthesis-Fmoc-strategy and were evaluated in the t...read more

Mentioned in this Paper

Analogs & derivatives
Anticonvulsants
Carbon
Epilepsy
Intravenous Infusion Procedures
Laboratory Procedures
Laboratory mice
Oxidation-Reduction
Peptides
Tyrosine
Paper Details
References
  • References39
  • Citations
1234
  • References39
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

Tissue Engineering

Tissue engineering is an interdisciplinary field that aims to create, repair, and/or replace tissues and organs by using biomaterial scaffolds, growth factors, stem cells, and genetic engineering. Discover the latest research on tissue engineering here.

Angelman Syndrome

Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.

Pain & Addiction

Chronic pain and addictive disorders present significant medical and public health problems; both are underdiagnosed and inadequately treated. The cooccurrence of pain and addiction adds complexity to the assessment and treatment of both disorders. Discover the latest reserch on pain and addiction here.

Tissue Therapy & Scaffolds

Tissue engineering aims to create, repair, and/or replace tissues and organs by using biomaterial scaffolds, growth factors, stem cells, and genetic engineering. Here is the latest research on biomaterial scaffolds that can be used for tissue therapy.

Epilepsy

Epilepsy is a chronic neurological disorder characterized by unprovoked and recurrent seizures. Discover the latest research on factors and mechanisms that underlie epilepsy here.

© 2019 Meta ULC. All rights reserved

Synthesis, characterization and anticonvulsant activity of new series of N-modified analogues of VV-hemorphin-5 with aminophosphonate moiety

Amino Acids

Nov 1, 2019

Petar T TodorovNadezhda Todorova

PMID: 31576456

DOI: 10.1007/s00726-019-02789-0

Abstract

A new series of N-modified analogues of the VV-hemorphin-5 with aminophosphonate moiety have been synthesized, characterized and investigated for anticonvulsant activity. The novel peptide analogues were prepared by solid-phase peptide synthesis-Fmoc-strategy and were evaluated in the t...read more

Mentioned in this Paper

Analogs & derivatives
Anticonvulsants
Carbon
Epilepsy
Intravenous Infusion Procedures

Related Papers

Paper Details
References
  • References39
  • Citations
1234
  • References39
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Get paper from

/papers/synthesis-characterization-and-anticonvulsant/31576456