Synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones through copper-catalyzed tandem reactions of N-(2-haloaryl)propiolamides with sodium azide

Organic Letters
Jiajie YanQian Cai

Abstract

A simple and efficient approach for the synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones is described. The methodology is based on a tandem reaction of 1-(2-haloaryl)propiolamides with sodium azide through a [3 + 2] azide-alkyne cycloaddition and intramolecular Ullmann-type C-N coupling process.

References

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Sep 29, 2011·Chemistry, an Asian Journal·Sandip G AgalaveVandana S Pore

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Citations

Nov 14, 2013·Organic Preparations and Procedures International·Hao Lin, Dianqing Sun
Apr 1, 2014·The Journal of Organic Chemistry·Ren-Long LiHai-Ming Guo
Dec 21, 2013·The Journal of Organic Chemistry·Jordan D GoodreidRobert A Batey

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