Synthesis of 3-bromosubstituted pyrroles via palladium-catalyzed intermolecular oxidative cyclization of bromoalkynes with N-allylamines

Chemical Communications : Chem Comm
Jia ZhengHuanfeng Jiang

Abstract

This paper describes a novel palladium-catalyzed oxidative cyclization of bromoalkynes with N-allylamines via cascade formation of C-N and C-C bonds. During this process, the bromine atom was retained to form 3-bromo-pyrroles, which can undergo the subsequent structural modifications.

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