PMID: 6402992Feb 1, 1983Paper

Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture

Annals of the Rheumatic Diseases
J A SalmonB Cashman

Abstract

Specimens of human rheumatoid and nonrheumatoid synovial lining were maintained in nonproliferative organ culture for 20 hours. The culture fluids were then assayed for prostaglandin E(2) (PGE(2)), thromboxane B(2) (TXB(2)), and 6-keto-prostaglandin F(1alpha) (6-keto-PGF(1alpha)) by specific radioimmunoassay. The presence of each of these substances was confirmed by gas chromatography and mass spectrometry. Rheumatoid tissue produced significantly more of each cyclo-oxygenase product than nonrheumatoid tissue.

References

Mar 1, 1978·Prostaglandins·J A Salmon
Aug 1, 1978·Annals of the Rheumatic Diseases·R A SturgeJ Morley
Jan 1, 1977·Scandinavian Journal of Rheumatology·L E TrangO Lövgren
Sep 1, 1970·The Journal of Clinical Endocrinology and Metabolism·T M el-Attar
Jan 1, 1959·Experimental Cell Research·O A TROWELL
Dec 15, 1951·Journal of the American Medical Association·R H FREYBERGC H ADAMS

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Citations

Nov 1, 1989·Agents and Actions·E MoilanenH Vapaatalo
Jan 1, 1983·Progress in Histochemistry and Cytochemistry·B Henderson
Apr 1, 1996·Australian Veterinary Journal·K T GibsonT Whittem
Apr 1, 1989·Annals of the Rheumatic Diseases·H Gonzalez-BuriticaG R Hughes
Jul 1, 1989·Annals of the Rheumatic Diseases·H Gonzalez-BuriticaR A Turner
Nov 29, 2005·Veterinary Immunology and Immunopathology·Hui-Wen ChangVictor F Pang
Oct 1, 1993·Pain·Hans-Georg Schaible, Blair D Grubb
Aug 4, 1999·Critical Reviews in Clinical Laboratory Sciences·E Kaiser
Dec 26, 2001·International Immunology·Xiaowen HeJohn M Stuart
Oct 1, 1988·The Journal of Pathology·K I Williams, G A Higgs
Aug 1, 1983·British Journal of Pharmacology·G A HiggsK Seager
Mar 4, 2000·Laboratory Investigation; a Journal of Technical Methods and Pathology·K MigitaK Eguchi
Jun 1, 1994·Arthritis and Rheumatism·K N GoldJ J Goronzy
Jan 1, 1986·Progress in Lipid Research·G A Higgs
Aug 1, 1985·Seminars in Arthritis and Rheumatism·B Henderson, E R Pettipher
Oct 1, 1990·Clinical Biochemistry·E KaiserK Zaky

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