PMID: 639803Mar 15, 1978Paper

Synthesis of cellulose precursors. The involvement of lipid-linked sugars

European Journal of Biochemistry
H E HoppR Pont Lezica

Abstract

Particulate preparations from the Chlorophyta Prototheca zopfi catalyze the incorporation of [14C]glucose from UDP-[14C]glucoe into lipids. These lipids have been characterized as lipid-P-glucose, lipid-PP-glucose, and lipid-PP-oligosaccharides. The lipid-linked oligosaccharides were a mixture ranging from a disaccharide to approximately a decasaccharide. Cellulase digestion and periodate oxidation showed that the oligosaccharides seem to be built of beta-1,4-linked glucoses. The lipid moiety had the properties of dolichol. The glucolipids described appeared as precursors of a water-soluble polymer. Treatments of this polymer with hydrolytic enzymes and periodate oxidation that it could be a glycoprotein containing beta-1,4-linked glucoses. When GDP-glucose was added to the incubation mixture, the 14C-labelled soluble polymer became insoluble in hot alkali. This insoluble polymer had the properties expected for cellulose. A scheme is proposed with the reactions involved in the initiation of cellulose biosynthesis.

References

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Citations

Jan 1, 1979·Journal of Supramolecular Structure·D S BaileyG Maclachlan
Jan 1, 1990·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·M N Horst
Nov 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·M BenzimanK M Cooper
Jul 1, 1979·European Journal of Biochemistry·B C BaguleyW Wehrli
Jul 1, 1979·European Journal of Biochemistry·M DürrG MacLachlan
Feb 16, 1987·European Journal of Biochemistry·L A Rivas, R Pont Lezica
May 10, 2000·Bioscience, Biotechnology, and Biochemistry·H M KooY S Kim
Oct 15, 1980·Archives of Biochemistry and Biophysics·R O CousoM A Dankert
Feb 16, 1987·European Journal of Biochemistry·L A Rivas, R Pont Lezica
Oct 1, 1989·The Journal of Experimental Zoology·M N Horst
Apr 1, 1982·CRC Critical Reviews in Biochemistry·R J Staneloni, L F Leloir
Sep 11, 1987·Biochimica Et Biophysica Acta·K Torossian, G Maclachlan
Nov 1, 1979·Archives of Biochemistry and Biophysics·P L Carlo, C L Villemez

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