Synthesis of CT images from digital body phantoms using CycleGAN

International Journal of Computer Assisted Radiology and Surgery
Tom RussKhanlian Chung

Abstract

The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms. The image quality was assessed in terms of anatomical accuracy and realistic noise properties. We performed two studies exploring various network and training configurations as well as a task-based adaption of the corresponding loss function. The CycleGAN using the Res-Net architecture and three XCAT input slices achieved the best overall performance in the configuration study. In the task-based study, the anatomical accuracy of the generated synthetic CTs remained high ([Formula: see text] and [Formula: see text]). At the same time, the generated noise texture was close to real data with a noise power spectrum correlation coefficient of [Formula: see text]. Simultaneously, we observed an improvement in annotation accuracy of 65% when using the dedicated loss function. The feasibility of a combined training on both real and synthetic data...Continue Reading

References

Sep 21, 2004·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Zhou WangEero P Simoncelli
Oct 23, 2010·Medical Physics·W P SegarsB M W Tsui
Feb 5, 2011·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Lin ZhangDavid Zhang
Aug 22, 2012·IEEE Transactions on Visualization and Computer Graphics·John ClyneAlan Norton
Aug 5, 2017·Medical Image Analysis·Geert LitjensClara I Sánchez
Oct 6, 2017·IEEE Transactions on Medical Imaging·Pedro CostaAurelio Campilho
Jun 12, 2018·Proceedings of SPIE·Camilo BermudezBennett A Landman
Dec 17, 2018·Zeitschrift für medizinische Physik·Alexander Selvikvåg Lundervold, Arvid Lundervold
Feb 18, 2019·Zeitschrift für medizinische Physik·Alena-Kathrin SchnurrFrank G Zöllner

❮ Previous
Next ❯

Citations

Oct 11, 2019·Magma·Frank G ZöllnerPeter Rogelj
Apr 7, 2020·Physics in Medicine and Biology·Hasib Zunair, A Ben Hamza
Nov 23, 2020·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Felix S L ThomsenJan Borggrefe
Mar 2, 2021·Social Network Analysis and Mining·Hasib Zunair, A Ben Hamza
Apr 24, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jelmer M WolterinkIvana Išgum
May 3, 2021·International Journal of Computer Assisted Radiology and Surgery·Dominik F BauerAlena-Kathrin Golla
Jun 18, 2021·Radiology. Artificial Intelligence·YiRang ShinYoung Han Lee
Aug 31, 2021·Journal of Imaging·Elena MorottiElena Loli Piccolomini
Dec 4, 2021·NPJ Breast Cancer·Asma BaccoucheAdel S Elmaghraby

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Computer Assisted Radiology and Surgery
Oleksandra TmenovaLuc Duong
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Samaneh KazemifarAmir Owrangi
International Journal of Computer Assisted Radiology and Surgery
Marco VidottoSara Moccia
© 2021 Meta ULC. All rights reserved