Synthesis of dual-phase Ti3O5/Ti4O7 nanofibers for efficient adsorption of SARS-CoV-2.

Materials Letters
Zhanlin DingMeiqing Sun

Abstract

In this study, we synthesized the dual-phase Ti3O5/Ti4O7 nanofibers for efficient adsorption of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a life-threatening virus being taking millions of people lives. The Ti3O5/Ti4O7 nanofibers were synthesized by preparation of H2Ti3O7 precursor, polydopamine coating and furnace calcination. Protein and phospholipid adsorption assays showed that the dual-phase nanofibers had much higher affinity to both the model molecules bovine serum album (BSA) and phosphatidylethanolamine (PE) than the control single-phase Ti6O11 nanofibers. Consistently, the dual-phase nanofibers exhibited much stronger adsorption ability to SARS-CoV-2 pseudovirus than Ti6O11. This study sheds a light on titanium oxide nanomaterials to adsorb SARS-CoV-2 for avoiding its infection and for capturing it during rapid virus detection.

References

Mar 11, 2020·Cell·Alexandra C WallsDavid Veesler
Apr 1, 2020·Nature·Jian ShangFang Li
May 8, 2020·Proceedings of the National Academy of Sciences of the United States of America·Jian ShangFang Li
May 8, 2020·Nanomedicine·Ghazal NikaeenSaeed Yousefinejad
May 22, 2020·Nature·Hauke S HillenPatrick Cramer
May 29, 2020·Science·Kimberly A PratherRobert T Schooley
Jun 13, 2020·The New England Journal of Medicine·Aki SakuraiYohei Doi

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