Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides

Organic Letters
Shreesha V BhatPallavi Sharma

Abstract

An unprecedented intermolecular cyclizative capture of the cyanamide anion and several nitrile oxides enables the synthesis of oxadiazol-5-imines.

References

Jan 1, 1979·Pharmacological Research Communications·E TremoliO Mantero
Mar 5, 2008·The Journal of Chemical Physics·Jeng-Da Chai, Martin Head-Gordon
May 7, 2009·Drug Discovery Today·Allan M Jordan, Stephen D Roughley
May 8, 2010·Chemical Communications : Chem Comm·Christian SpiteriJohn E Moses
Dec 7, 2010·Angewandte Chemie·Pazhamalai AnbarasanMatthias Beller
Nov 11, 2011·Clinical Therapeutics·Kathy Zaiken, Judy W M Cheng
Nov 26, 2011·The Annals of Pharmacotherapy·William L Baker, William B White
May 26, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Yesim Saniye Kara

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Citations

Oct 6, 2016·Organic Letters·Xiaolong YuJin Zhu
Apr 19, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·M R Ranga PrabhathPallavi Sharma
Jul 1, 2017·Organic Letters·James N AyresLouis C Morrill
Sep 14, 2018·Organic & Biomolecular Chemistry·Manthena Chaitanya, Pazhamalai Anbarasan

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